Kristen M . Drescher, PhD

Department

Med. Microbiology & Immunology

Position

Professor

Books

• Maresso Karen Colbert, Prevention and Screening Risk Factors, Screening, and Chemoprevention [Book Chapter] 2014
• RNA Technologies and Their Applications, RNA Technologies
  Liu Jun, MicroRNAs in Epithelial Antimicrobial Immunity [Book Chapter] 2010
• Group B Coxsackieviruses
  Oberste Steven, Group B Coxsackieviruses [Book Chapter] 2008
• Group B Coxsackieviruses
  Drescher Kristen M., The CVB and etiology of type 1 diabetes [Book Chapter] 2008
• How Do We Best Employ Animal Models for Type 1 Diabetesand Multiple Sclerosis
  Tracy Steven, Coxsackievirus infections and NOD mice [Book Chapter] 2007

Articles

• Kanno Toru, Erratum 2006

Publications

• Journal of visualized experiments
  Nguyen Brian T., Transfection of a Molecular Clone of Naegleria gruberi rDNA into N. gruberi Trophozoites 2024
• Microbiology resource announcements
  Nguyen Brian T, Complete sequence of the closed circular extrachromosomal element of Naegleria pringsheimi De Jonckheere (strain Singh), p. e0080623 2024
• Microbiology resource announcements
  Nguyen Brian T., Complete sequence of the closed circular extrachromosomal element (CERE) of Naegleria australiensis De Jonckheere (strain PP 397) 2023
• Nutrients
  Law David, Creatine and Resistance Training: A Combined Approach to Attenuate Doxorubicin-Induced Cardiotoxicity
  15:18, p. 4048 2023
• Microbiology resource announcements
  Nguyen Brian T, Complete Sequence of the Closed Circular Extrachromosomal Element of Naegleria jadini Willaert and Ray (Strain ITMAP400), p. e0006123 - e0006123 2023
• Nature communications
  Deng Silu, Cryptosporidium uses CSpV1 to activate host type I interferon and attenuate antiparasitic defenses
  14:1, p. 1456 - 17 2023
• Medicine and science in sports and exercise
  Bredahl Eric C., Controlled Metabolic Depression With Adenosine Receptor Agonists
  54:9S, p. 670 - 670 2022
• Medicine and science in sports and exercise
  Johnson Niklas, Effects Of Creatine Supplementation On The Viability Of Walker 256 Mammary Carcinomas
  54:9S, p. 607 - 607 2022
• Journal of Neuroinflammation
  Mathy Nicholas W., A novel long intergenic non-coding RNA, Nostrill, regulates iNOS gene transcription and neurotoxicity in microglia
  18:1 2021
• Plasmid
  Nguyen B. T., The extrachromosomal elements of the Naegleria genus
  115 2021
• Nutrients
  Bredahl Eric C., The role of creatine in the development and activation of immune responses
  13:3, p. 1 - 17 2021
• Nutrition and Cancer
  Bredahl Eric Christopher, Use of Creatine and Creatinine to Minimize Doxorubicin-Induced Cytotoxicity in Cardiac and Skeletal Muscle Myoblasts
  73:11-12, p. 2597 - 2604 2021
• Microbiology Resource Announcements
  Mullican John C., Complete genome sequence of the naegleria fowleri (strain lee) closed circular extrachromosomal ribosomal DNA element
  9:49 2020
• Medicine & Science in Sports & Exercise
  BREDAHL ERIC C., Resistance training during chemotherapy with doxorubicin
  52:12, p. 2529 - 2537 2020
• Medicine and Science in Sports and Exercise
  Bredahl Eric C., Resistance Training during Chemotherapy with Doxorubicin
  52:12, p. 2529 - 2537 2020
• Medicine and science in sports and exercise
  Najdawi Wisam, The Effect Of Doxorubicin On Myocardial Extracellular Matrix Degradation: 951 Board #185 May 29 3:30 PM - 5:00 PM
  51:6 Suppl, p. 245 - 245 2019
• Medicine and science in sports and exercise
  Legenza Ashton, The Effects of Resistance Training On Cardiac Muscle Function During Cancer Cachexia
  51:6S, p. 613 - 613 2019
• Antimicrobial agents and chemotherapy
  Pandya Amit N., Indole-2-carboxamides are active against mycobacterium abscessus in a mouse model of acute infection
  63:3 2019
• Cytokine
  Riesberg Lisa A., Creatinine downregulates TNF-α in macrophage and T cell lines
  110, p. 29 - 38 2018
• Medicine & Science in Sports & Exercise
  Kaufenberg Mikayla, Effect of Resistance Training on Contractile Force Production during Doxorubicin-Treatment
  50:5S, p. 644 - 644 2018
• Medicine & Science in Sports & Exercise
  Bredahl Eric, The effect of creatine and creatinine on myocellular injury in doxorubicin-treated skeletal muscle myoblasts
  50:5S, p. 644 - 644 2018
• Scientific American
  Drescher Kristen M., Medicine van quishing diabetes
  318:2, p. 54 - 59 2018
• Medicine and science in sports and exercise
  Eckerson Joan M., The Effect of Creatine Supplementation on Upper Body Strength and Immune Function in Men
  49:5S, p. 1027 2017
• Medicine & Science in Sports & Exercise
  Bredahl Eric C., The Effects Of Creatine And Creatinine On Rates Of Apoptosis In Doxorubicin-treated Myoblasts
  49:5S, p. 7 - 7 2017
• International Immunopharmacology
  Riesberg Lisa A., Beyond Muscles: The Untapped Potential of Creatine
  37, p. 31 - 42 2016
• Journal of Immunology
  Hu Guoku, LincRNA-Cox2 Promotes Late Inflammatory Gene Transcription in Macrophages through Modulating SWI/SNF-Mediated Chromatin Remodeling
  196:6, p. 2799 - 2808 2016
• Reviews in Medical Virology
  Drescher Kristen M., Enteroviruses, hygiene and type 1 diabetes: toward a preventive vaccine
  25:1, p. 19 - 32 2015
• Current Treatment Options in Oncology
  Lynch Henry T., Genetics, biomarkers, hereditary cancer syndrome diagnosis, heterogeneity and treatment: a review
  15:3, p. 429 - 442 2014
• Journal of Microbiological Methods
  Smithee Shane, A novel, broadly applicable approach to isolation of fungi in diverse growth media
  105, p. 155 - 161 2014
• Journal of Neuroimmunology
  Drescher Kristen M., miR-684 regulation of neurexophilin-1 and alpha-neurexin expression
  253:2-Jan, p. 63 - 63 2012
• Frontiers in Genetics
  Hu Guoku, Exosomal microRNAs: biological properties and therapeutic potential.
  3, p. 56 2012
• PLoS One
  Zhou Rui, miR-16 Targets Transcriptional Corepressor SMRT and Modulates NF-kappaB-Regulated Transactivation of Interleukin-8 Gene
  7:1, p. e30772 2012
• Journal of Antibiotics
  McDonald Thomas, Creatinine inhibits bacterial replication
  65:3, p. 153 - 156 2012
• Diabetes/Metabolism Research and Reviews
  Tracy Steven, Enteroviruses and type 1 diabetes
  27:8, p. 820 - 823 2011
• Grün K, Heterotopic rat heart transplantation: Accumulation of Ubiquinone in the rat heart allograft depends on ischemia/reperfusion 2011
• International Immunopharmacology
  Leland Korey M., Effect of creatine, creatinine, and creatine ethyl ester on TLR expression in macrophages
  11:9, p. 1341 - 1347 2011
• Reviews in Medical Virology
  Tracy S., Enteroviruses, type 1 diabetes and hygiene
  20:2, p. 106 - 116 2010
• Journal of Infectious Diseases
  Gong Ai-Yu, Cryptosporidium parvum Induces B7-H1 Expression in Cholangiocytes by Down-Regulating MicroRNA-513
  201:1, p. 160 - 169 2010
• Clinical & developmental immunology
  Drescher Kristen M., Current hypotheses on how microsatellite instability leads to enhanced survival of lynch syndrome patients
  2010, p. 170432 2010
• PLoS Pathogens
  Zhou Rui, NF-kappaB p65-dependent transactivation of miRNA genes following Cryptosporidium parvum infection stimulates epithelial cell immune responses
  5:12, p. e1000681 2009
• Familial Cancer
  Drescher Kristen M., Lymphocyte recruitment into the tumor site is altered in patients with MSI-H colon cancer
  8:3, p. 231 - 239 2009
• The Journal of immunology (1950)
  Drescher Kristen M., Impact of TLR deletion on brain pathology in a mouse model of encephalitis (128.22)
  182:1_Supplement, p. 128 - 128.22 2009
• International Reviews of Immunology
  Liu Jun, MicroRNAs and Epithelial Immunity
  28:4-Mar, p. 139 - 154 2009
• Virology
  Chapman Nora M., 5′ terminal deletions in the genome of a coxsackievirus B2 strain occurred naturally in human heart
  375:2, p. 480 - 491 2008
• Gastroenterology
  Lynch Henry T., Immunology and the lynch syndrome
  134:4, p. 1246 - 1249 2008
• Annals of the New York Academy of Sciences
  Drescher Kristen M., Establishment of a model to examine the early events involved in the development of virus-induced demyelinating lesions
  1103, p. 152 - 156 2007
• Virology
  Drescher Kristen M., Injection of the sciatic nerve with TMEV
  359:1, p. 233 - 242 2007
• Sonnino Roberta E., Partnership between a SOM - based Women in Medicine and Science and Minority Faculty Development programs and AAMC: Getting the message across 2006
• Journal of Virology
  Kanno Toru, Group B coxsackievirus diabetogenic phenotype correlates with replication efficiency
  80:11, p. 5637 - 5643 2006
• Current Topics in Microbiology and Immunology
  Tracy S., Evolution of virulence in picornaviruses
  299, p. 193 - 209 2006
• Clinical and Applied Immunology Reviews
  Drescher Kristen M., Tumor infiltrating lymphocytes (TILs): Lessons learned in 30 years of study
  5:3, p. 149 - 166 2005
• Journal of General Virology
  Lee C. K., Characterization of an infectious cDNA copy of the genome of a naturally occurring, avirulent coxsackievirus B3 clinical isolate
  86:1, p. 197 - 210 2005
• Virology
  Drescher Kristen M., Coxsackievirus B3 infection and type 1 diabetes development in NOD mice
  329:2, p. 381 - 394 2004
• Journal of Neuroscience
  Pavelko Kevin D., Interleukin-6 protects anterior horn neurons from lethal virus-induced injury
  23:2, p. 481 - 492 2003
• Journal of Virology
  Tracy S., Toward testing the hypothesis that Group B Coxsackieviruses (CVB) trigger insulin-dependent diabetes: inoculating nonobese diabetic mice with CVB markedly lowers diabetes incidence
  76:23, p. 12097 - 12111 2002
• Journal of Neurovirology
  Drescher Kristen M., ICAM-1 is crucial for protection from TMEV-induced neuronal damage but not demyelination
  8:5, p. 452 - 458 2002
• Drescher K, Effect of belaperidone on cholinergic activity in rat prefrontal cot nucleus accumbens and corpus striatum - interaction with methamphetamine 2001
• Molecular and Cellular Neurosciences
  Pavelko Kevin D., HLA-DQ polymorphism influences progression of demyelination and neurologic deficits in a viral model of multiple sclerosis
  15:6, p. 495 - 509 2000
• Journal of Immunology
  Drescher Kristen M., TGF-β2 reduces demyelination, virus antigen expression, and macrophage recruitment in a viral model of multiple sclerosis
  164:6, p. 3207 - 3213 2000
• International immunology
  Drescher K, V sub( beta )8 super(+) T cells protect from demyelinating disease in a viral model of multiple sclerosis
  12:3, p. 271 - 280 2000
• Human Immunology
  Das Pritam, Complementation between specific HLA-DR and HLA-DQ genes in transgenic mice determines susceptibility to experimental autoimmune encephalomyelitis
  61:3, p. 279 - 289 2000
• Brain Pathology
  Drescher Kristen M., CD40L is critical for protection from demyelinating disease and development of spontaneous remyelination in a mouse model of multiple sclerosis
  10:1, p. 1 - 15 2000
• International Immunology
  Drescher Kristen M., V(β)8+ T cells protect from demyelinating disease in a viral model of multiple sclerosis
  12:3, p. 271 - 280 2000
• Experimental Neurology
  McGavern Dorian B., Quantitative assessment of neurologic deficits in a chronic progressive murine model of CNS demyelination
  158:1, p. 171 - 181 1999
• Brain Pathology
  Drescher Kristen M., CNS cell populations are protected from virus-induced pathology by distinct arms of the immune system
  9:1, p. 21 - 31 1999
• Journal of neuroimmunology
  Das P., HLA-Dr is critical for the induction of EAE, while HLA-DQ can modulate the severity of disease: Studies in HLA transgenic mice
  90:1, p. 62 - 62 1998
• Journal of Neuroimmunology
  Drescher Kristen M., Failure of treatment with Linomide or oral myelin tolerization to ameliorate demyelination in a viral model of multiple sclerosis
  88:1-2, p. 111 - 119 1998
• Journal of Clinical Investigation
  Drescher Kristen M., Expression of the human histocompatibility leukocyte antigen DR3 transgene reduces the severity of demyelination in a murine model of multiple sclerosis
  101:8, p. 1765 - 1774 1998
• Immunological Reviews
  Drescher Kristen M., Antiviral immune responses modulate the nature of central nervous system (CNS) disease in a murine model of multiple sclerosis
  159, p. 177 - 193 1997
• Virology
  Drescher Kristen M., Evidence for induction of interferon-α and interferon-β in retinal glial cells of Muller
  234:2, p. 309 - 316 1997
• Investigative Ophthalmology and Visual Science
  Drescher Kristen M., Herpes simplex virus type 1 alters transcript levels of tumor necrosis factor-α and interleukin-6 in retinal glial cells
  37:11, p. 2302 - 2312 1996
• Journal of Neuroimmunology
  Drescher Kristen M., Modulation of immune-associated surface markers and cytokine production by murine retinal glial cells
  64:1, p. 71 - 81 1996
• Memórias do Instituto Oswaldo Cruz
  Drescher K. M., Response of drug resistant isolates of Schistosoma mansoni to antischistosomal agents.
  88:1, p. 89 - 95 1993

Presentations

• Presentation for the Health Sciences Educator Development Program How to Improve Your Teaching: Insight From the Evaluation Committee 2015
• Drescher, KM and Tracy, SM Injection of the Sciatic Nerve with Theilers Virus: A Model of Virus-Induced Peripheral Demyelination; Positive Strand Meeting; Washington DC (poster) 2007
• Tracy, SM and Drescher, KM COXSACKIEVIRUS AND NOD MICE: RELEVANT MODELS OF PROTECTION FROM, AND INDUCTION OF, TYPE 1 DIABETES 2006
• Drescher, KM and Tracy, SM Establishment of a model to examine the events involved in the development of virus-induced demyelinating lesions. NY Acad Sciences, Animal Models of MS and TID, San Franscisco 2006
• National Multiple Sclerosis Society - Nebraska Chapter; TRENDS meeting; Roundtable Discussion on Research 2006
• Drescher KM and Tracy S Coxsackie B virus replication in pancreatic islets: virus associates with the four major islet cell types, not merely beta cells American Society of Virology, Madison, WI. 2006
• 6. Tracy, S.M., Drescher, K.M., Jackson, J.D., Sanderson, S Vaccinating NOD mice against CVB-induced rapid T1D onset: type-specific immunity is not required to lower T1D incidence American Society of Virology, Madison, WI. 2006
• Neuregulins in the peripheral nervous system in virus infections and autoimmune disease 2006
• Role of C3 in a model of virus-induced encephalitis 2006
• Impact of C3 deletion in a mouse model of virus induced demyelinating disease UNMC Department of Cell Biology and Genetics 2006
• Birth of a successful women in medicine and science program in a private, Jesuit medical school; R.E. Sonnino, M. Gentry-Nielsen, K.M. Drescher, M. Schofield, A. Chatterjee; AAMC Meeting 2005
• Neuregulin is upregulated in the sciatic nerve following infection with TMEV; KM Drescher, A Heller, S Tracy; International Congress of Virology 2005
• Group B Coxsackievirus infections in NOD mice: Towards clarifying a role of enteroviruses in human type 1 diabetes onset, S, Tracy and K. Drescher, International Congress of Virology 2005
• American College of Cardiology 2005
• Hounsfield Lecture (Imperial College, London) Developing A Novel Ultrasound Method Of Imaging Molecular Activities Dr J Yeh Dr C Sennoga Prof M Blomley Mr P Muckett Dr R Eckersley Prof S Tracy Dr K Drescher Dr YW Li Dr C Tang Dr J Boyle Dr J Mason8 Dr S Nourshargh Prof J Seddon Prof D Haskard Dr P Nihoyannopoulos 2005
• America's Conference on the Treatment and Immunology of Multiple Sclerosis 2004
• CVB-induces diabetes in older NOD mice; SM Tracy, KM Drescher, K Kono, S Bopegamage, SD Carson 2004
• International Congress on Immunology 2004
• Coxsackie B virus replicates in islets of old NOD mice and initiates type 1 diabetes. Steven Tracy, Kristen M. Drescher, Ken Kono, Steven D. Carson, Shubhada Bopegamage; Seventh International Symposium on positive-strand RNA viruses; San Francisco, CA 2004
• Paula Kocakova and Kristen M. Drescher C3 is required for efficient clearance of virus from the brains of TMEV-infected mice; Federation of the American Society of Experimental Biology 2004
• Cary M. Wolter,Jill R. Fuhrman, and Kristen M. Drescher Localization of matrix metalloproteinases (MMPs) in the brains of TMEV-infected mice Midwest Medical Student Research Forum (poster) 2004
• Oshunleti, O. and Drescher, K.M. Use of CVB chimeric viruses as vaccine vectors in an animal model of multiple sclerosis - National Medical Fellowship Program 2004
• Paula Kocakova and Kristen M. Drescher C3 is required for efficient clearance of virus from the brains of TMEV-infected mice, Midwest Medical Student Research Forum 2004
• Immunology Group - Use of CVB chimerae as vaccines in a model of multiple sclerosis 2002
• Johnson, T.D., Marsh, L.B., Ray, T., Drescher, K.M. The relative contribution of B cells and complement in protection of the brain from Theiler's murine encephalomyelitis virus. Minority summer student poster session 2002
• Tracy et al, X!!th International COngress of Virology 2002
• Modulation of activin/inhibin mRNA levels following TMEV infection XIIth International Congress of Virology (Paris, France) 2002
• Theiler's Virus model of multiple sclerosis 2002
• Ukpo,O.C., S.E. Hopkins and K.M. Drescher. Identification of apoptotic cells in the brains and spinal cords of TMEV-infected mice. Minority Summer Student Research Forum (Poster) 2001
• Hopkins, S.E., O.C. Ukpo, and K.M. Drescher. Apoptosis in the brains of TMEV-infected C57BL6/J and B10.Q mice. Minority High School Student Research Forum (Poster). 2001
• Texas A & M University - Neuroscience Seminar Series 2001
• University of Nebraska Medical Center - Department of Cell Biology and Anatomy 2001
• Cooper, D.M. and Drescher, K.M. - Regional ASM Meeting - oral presentation 2001
• University of Nebraska Medical Center - Immunology Interest Group 2001
• Cooper, D.C. and Drescher, K.D. Midwest Student Research Forum - poster 2001
• Cooper, D.M. and Drescher, K.D. - Regional AAAS Meeting - poster 2000
• Flores, N., Cooper, D.M. and Drescher, K.M. - Minority summer student poster session 2000
• 10/22/99;VA Hospital;"Expression of the HLA-DR3 Transgene reduces the severity of demyelination in a viral model of multiple sclerosis" 1999

Other

• Defining the Origin of Replication in Naegleria gruberi

• Defining the Origin of Replication in Naegleria gruberi

Awards

• National Award
  Jr. Investigator Award
  NY Academy of Sciences