Tal Teitz, PhD

Department

Pharmacology and Neuroscience

Position

Associate Professor

Books

• Methods in Molecular Biology
  Teitz Tal, Development of cell-based high-throughput chemical screens for protection against cisplatin-induced ototoxicity [Book Chapter] 2016

Articles

• Xu Heng, Erratum 2015

Publications

• Clinical and translational medicine
  Sailor-Longsworth Emma J., Oseltamivir (Tamiflu), a commonly prescribed antiviral drug, mitigates hearing loss in mice
  14:8, p. e1803 2024
• International journal of molecular sciences
  Lutze Richard D., ERK1/2 Inhibition via the Oral Administration of Tizaterkib Alleviates Noise-Induced Hearing Loss While Tempering down the Immune Response
  25:12, p. 6305 2024
• Pharmaceuticals (Basel, Switzerland)
  Lutze Richard D., Trametinib, a MEK1/2 Inhibitor, Protects Mice from Cisplatin- and Noise-Induced Hearing Loss
  17:6, p. 735 2024
• Journal of the American Society of Nephrology
  Pushpan Chithra K., Repurposing AZD5438 and Dabrafenib for Cisplatin-Induced Acute Kidney Injury 2023
• JCI insight
  Ingersoll Matthew A, Dabrafenib protects from cisplatin-induced hearing loss in a clinically relevant mouse model 2023
• Journal of Medicinal Chemistry
  Hazlitt Robert A., Development of Second-Generation CDK2 Inhibitors for the Prevention of Cisplatin-Induced Hearing Loss
  61:17, p. 7700 - 7709 2018
• Journal of Experimental Medicine
  Teitz Tal, CDK2 inhibitors as candidate therapeutics for cisplatin- and noise-induced hearing loss
  215:4, p. 1187 - 1203 2018
• Nature genetics
  Xu Heng, Common variants in ACYP2 influence susceptibility to cisplatin-induced hearing loss
  47:3, p. 263 - 266 2015
• Cancer Research
  Teitz Tal, Th-MYCN mice with caspase-8 deficiency develop advanced neuroblastoma with bone marrow metastasis
  73:13, p. 4086 - 4097 2013
• PloS one
  Teitz Tal, Preclinical models for Neuroblastoma
  6:4 2011
• Cancer Research
  Barbero Simone, Caspase-8 association with the focal adhesion complex promotes tumor cell migration and metastasis
  69:9, p. 3755 - 3763 2009
• Cancer Research
  Lahti Jill M., Does integrin-mediated cell death confer tissue tropism in metastasis?
  66:12, p. 5981 - 5984 2006
• Cell Cycle
  Teitz Tal, Halting neuroblastoma metastasis by controlling integrin-mediated death
  5:7, p. 681 - 685 2006
• Nature
  Stupack Dwayne G., Potentiation of neuroblastoma metastasis by loss of caspase-8
  439:7072, p. 95 - 99 2006
• Nature medicine
  Kidd Vincent J, Reply to 'Expression and methylation of CASP8 in neuroblastoma: Identification of a promoter region'
  8:12, p. 1335 - 1335 2002
• Banelli Barbara, Expression and methylation of CASP8 in neuroblastoma 2002
• Oncogene
  Teitz Tal, Caspase-9 and Apaf-1 are expressed and functionally active in human neuroblastoma tumor cell lines with 1p36 LOH and amplified MYCN
  21:12, p. 1848 - 1858 2002
• Oncogene
  Takita Junko, Allelic imbalance on chromosome 2q and alterations of the caspase 8 gene in neuroblastoma
  20:32, p. 4424 - 4432 2001
• Journal of Molecular Medicine
  Teitz Tal, Aggressive childhood neuroblastomas do not express caspase-8
  79:8, p. 428 - 436 2001
• Nature Medicine
  Teitz Tal, Caspase 8 is deleted or silenced preferentially in childhood neuroblastomas with amplification of MYCN
  6:5, p. 529 - 535 2000
• Seminars in Cell and Developmental Biology
  Kidd Vincent J., Proteolytic regulation of apoptosis
  11:3, p. 191 - 201 2000
• Medical and Pediatric Oncology
  Takita Junko, Absent or reduced expression of the caspase 8 gene occurs frequently in neuroblastoma, but not commonly in Ewing sarcoma or rhabdomyosarcoma
  35:6, p. 541 - 543 2000
• Gene
  Grenet Jose, Structure and chromosome localization of the human CASP8 gene
  226:2, p. 225 - 232 1999
• Proceedings of the National Academy of Sciences of the United States of America
  Siegel D. S., Hexamethylene bisacetamide induces programmed cell death (apoptosis) and down-regulates BCL-2 expression in human myeloma cells
  95:1, p. 162 - 166 1998
• Investigative and Cell Pathology
  Teitz Tal, Thymic epithelial neoplasms in transgenic mice expressing SV40 T antigen under the control of an erythroid‐specific enhancer
  177:3, p. 309 - 315 1995
• Carcinogenesis
  Teitz T., Amplification of a sv40 t antigen transgene is associated with sarcomagenesis in mice
  15:9, p. 2049 - 2051 1994
• DNA and Cell Biology
  Teitz Tal, SV40 T Antigen Directed by a Powerful Erythroid Enhancer–Promoter Produced Sarcomas and Pancreatic Tumors But Not Erythroid-Specific Tumors in Transgenic Mice
  13:7, p. 705 - 710 1994
• Proceedings of the National Academy of Sciences of the United States of America
  Teitz T., Rhabdomyosarcoma arising in transgenic mice harboring the β-globin locus control region fused with simian virus 40 large T antigen gene
  90:7, p. 2910 - 2914 1993
• Genomics
  Yang-Feng Teresa L., Assignment of the human casein kinase II β-subunit gene to 6p12→p21
  8:4, p. 741 - 742 1990
• Mutation Research - DNA Repair
  Teitz Tal, Expression of the cDNA for the beta subunit of human casein kinase II confers partial UV resistance on xeroderma pigmentosum cells
  236:1, p. 85 - 97 1990
• Gene
  Teitz Tal, Isolation by polymerase chain reaction of a cDNA whose product partially complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells
  87:2, p. 295 - 298 1990
• Proceedings of the National Academy of Sciences of the United States of America
  Teitz T., Complementation of the UV-sensitive phenotype of a xeroderma pigmentosum human cell line by transfection with a cDNA clone library.
  84:24, p. 8801 - 8804 1987
• Somatic Cell and Molecular Genetics
  Canaani Dan, Immortalization of xeroderma pigmentosum cells by simian virus 40 DNA having a defective origin of DNA replication
  12:1, p. 13 - 20 1986

Presentations

• "Chemotherapy Drugs and Ototoxicity"- PIHL Group Meeting 2023
• Dual Effect: Kinase inhibitors AZD5438 and Dabrafenib Alleviate Cisplatin-Induced Acute Kidney Injury and Hearing Loss. Brainstorm Presentation at Creighton University, School of Medicine. 2022
• Bellucci 2022 Symposium on Aging and Age-related Hearing Loss-Dabrafenib, a BRAF Inhibitor Protects Against Cisplatin-Induced Kidney Injury and Hearing Loss. 2022
• Bellucci Symposia 2022- Repurposing Oseltamivir to Prevent Noise-induced hearing Loss. Regina Kelmann and Emma Sailor First co-authors. 2022
• Bellucci Symposium 2022- Repurposing FDA-approved MEK Inhibitor Trametanib for Protection from Cisplatin Induced Hearing Loss. 2022
• Bellucci Symposia 2022- Aging and Age-related Hearing Loss. ERK 1/2 Inhibitor Protects from Noise-induced Hearing Loss. 2022
• Tamiflu as a Therapeutic Candidate for Noise-Induced Hearing Loss- ARO Meeting 2022. 2022
• Development of New Pharmacologic Agents for Hearing Loss and Vestibular Pathology. Center for Comparative Evolutionary Biology of Hearing, Translational Research Day, University of Maryland, College Park, School of Medicine, Baltimore, MD, Dec 9, 2021. 2021
• Gave a presentation in the 5th Chinese Hearing Research Conference on our research studies , Beijing, China 2019, titled "Drug Development for Cisplatin- and Noise- induced Hearing Loss." 2019
• Research Rounds and Seminars at Department of Pharmacology and Neuroscience 2019
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