Ronald A . Shikiya, PhD

Department

Med. Microbiology & Immunology

Position

Research Assistant Professor

Books

• Prions and Diseases
  Shikiya Ronald A., Prion Strain Interference [Book Chapter] 2023
• Shikiya Ronald A, The Story of Prions’ Discovery 2014
• Prions and Diseases : Volume 1, Physiology and Pathophysiology
  Schutt Charles R., Prion strain interference [Book Chapter] 2013

Publications

• mBio
  Steadman Benjamin S., Minor prion substrains overcome transmission barriers, p. e0272124 2024
• PLoS pathogens
  Gunnels Tess, Evidence for preexisting prion substrain diversity in a biologically cloned prion strain
  19:9, p. e1011632 - e1011632 2023
• PLoS pathogens
  Block Alyssa J., Efficient interspecies transmission of synthetic prions
  17:July 2021
• mSphere
  Shikiya Ronald A., Failure to detect prion infectivity in ticks following prion-Infected blood meal
  5:5 2020
• Journal of Biological Chemistry
  Bourkas Matthew E.C., Engineering a murine cell line for the stable propagation of hamster prions
  294:13, p. 4911 - 4923 2019
• PLoS pathogens
  Eckland Thomas E., Independent amplification of co-infected long incubation period low conversion efficiency prion strains
  14:10 2018
• Plos Pathogens
  Shikiya Ronald A., PrPSc Formation and Clearance as Determinants of Prion Tropism
  13:3, p. e1006298 - e1006298 2017
• Journal of Virology
  Langenfeld Katie A., Incongruity between Prion Conversion and Incubation Period Following CoInfection
  90:12, p. 5715 - 5723 2016
• PLoS One
  Clouse Melissa D., Nasal Associated Lymphoid Tissue of the Syrian Golden Hamster Expresses High Levels of PrPC
  10:2, p. e0117935 (10 pages) 2015
• Prion
  Shikiya Ronald A., Prion formation, but not clearance, is supported by protein misfolding cyclic amplification
  8:6, p. 415 - 420 2014
• Journal of visualized experiments : JoVE
  Saunders Samuel E., Protein misfolding cyclic amplification of prions. 2012
• Journal of Virology
  Saunders Samuel E., Replication efficiency of soil-bound prions varies with soil type
  85:11, p. 5476 - 5482 2011
• Journal of Virology
  Shikiya R. A., In vitro generation of high titer prions
  85:24, p. 13439 - 13442 2011
• PLoS Pathogens
  Ayers J. I., The Strain-Encoded Relationship between PrP Replication, Stability and Processing in Neurons is Predictive of the Incubation Period of Disease
  7:3, p. e1001317 2011
• Journal of Virology
  Shikiya R. A., Co-infecting prion strains compete for a limiting cellular resource
  84:11, p. 5706 - 5714 2010

Presentations

• "PrPSc formation and clearance as determinants of prion tropism" Prion 2018 Santiago de Compostela, Spain 2018
• NES 510 Neurophysiology Lab, Guest Speaker. Creighton University. Omaha, NE 2018
• "Persistence of high titer prion strain in a prion strain mixture". INBRE 2017. August 6-8, 2017. 2017
• "Incongruity between prion conversion and incubation period following co-infection". Prion 2017. May 23-26, 2017. Edinburgh, Scotland. 2017
• NES 510 Neurophysiology Lab, Guest Speaker. Creighton University. Omaha, NE 2017
• PHY 353 Introduction to Biological Physics, Guest Speaker. Creighton University. Omaha, NE 2017
• "Restricted propagation of sheep scrapie in hamsters" Prion 2016. May 10-13, 2016. Tokyo, Japan. 2016
• "Prion formation, but not clearance, is supported by PMCA" Prion 2015. May 26-29. Fort Collins, CO 2015
• "Abundance of prion proteins in Lymphoreticular tissue". 2014 Nebraska Neuroscience Symposium. September 24th, 2014. Omaha, NE 2014
• "Absence of PrPSc clearance in PMCA". Expanding Prion Horizons 2013. October 16th-18th, 2013. Fort Collins, CO. 2013
• "Investigation of conversion efficiency between natural and in vitro generated prions". Expanding Prion Horizons 2013. October 16th-18th, 2013. Fort Collins, CO. 2013
• "Endogenous PrPC Levels in Hamster Lymphoid Tissue". Expanding Prion Horizons 2013. October 16th-18th, 2013. Fort Collins, CO 2013
• "Prion Strain Emergence". Neuro-Prion 2013 Annual Conference. May 26th-29th, 2013. Banff, Canada 2013
• "In Vitro Generation of High-Titer Prions". Neuro-Prion 2012 Annual Conference. May 9th-12th, 2012. Amsterdam, The Netherlands. 2012
• "The Strain-encoded Relationship Between PrPSc Replication, Stability and Processing in Neurons is Predictive of the Incubation Period of Disease". Neuro-Prion 2011 Annual Conference. May 17th-19th, 2011. Montreal, Canada 2011
• PHY 353 Introduction to Biological Physics, Guest Speaker. Creighton University. Omaha, NE 2011
• "Amplification Coefficient of Hamster Prion Strains". Neuro-Prion 2010 Annual Conference. September 8th-11th, 2010. Salzburg, Austria 2010
• PHY 353 Introduction to Biological Physics, Guest Speaker. Creighton University. Omaha, NE 2010
• "In vitro Prion Strain Interference". Neuro-Prion 2008 Annual Conference. October 8th-10th, 2008. Madrid, Spain. 2008
• "In vitro Amplification of Prion Strains". Neuro-Prion 2007 Annual Conference. September 24th-28th, 2007. Edinburgh, Scotland 2007