Laura A . Hansen, PhD

Department

Biomedical Sciences

Position

Professor

Books

• Reference Module in Biomedical Sciences
  Hansen Laura A., Squamous Cell Carcinoma of the Skin [Book Chapter] 2015
• Reference Module in Biomedical Sciences
  Hansen Laura A., Basal Cell Carcinoma [Book Chapter] 2015
• Reference Module in Biomedical Research
  Hansen Laura A., Mycosis Fungoides [Book Chapter] 2014
• Reference Module in Biomedical Research
  Hansen Laura A., Melanoma [Book Chapter] 2014
• xPharm: The Comprehensive Pharmacology Reference
  Hansen Laura A., Mycosis Fungoides [Book Chapter] 2011
• xPharm: The Comprehensive Pharmacology Reference
  Hansen Laura A., Skin Cancer [Book Chapter] 2011
• xPharm: The Comprehensive Pharmacology Reference
  Hansen Laura A., Melanoma [Book Chapter] 2011
• xPharm: The Comprehensive Pharmacology Reference
  Hansen Laura A., Basal Cell Carcinoma [Book Chapter] 2011
• xPharm: The Comprehensive Pharmacology Reference
  Hansen Laura A., Squamous Cell Carcinoma [Book Chapter] 2011
• Signaling Pathways in Squamous Cancer
  Repertinger Susan K., The Epidermal Growth Factor Receptor in Normal and Neoplastic Epithelia [Book Chapter] 2011

Publications

• Molecular biology reports
  Agrawal Swati, Regulation of pro-apoptotic and anti-apoptotic factors in obesity-related esophageal adenocarcinoma
  51:1, p. 1049 2024
• Biomarker research
  Fu Yusi, Transcriptomic changes and gene fusions during the progression from Barrett’s esophagus to esophageal adenocarcinoma
  12:1, p. 78 2024
• International journal of molecular sciences
  Kamayirese Seraphine, The Development of CDC25A-Derived Phosphoseryl Peptides That Bind 14-3-3ε with High Affinities
  25:9, p. 4918 2024
• ACS omega
  Kamayirese Seraphine, Optimizing Phosphopeptide Structures That Target 14-3-3ε in Cutaneous Squamous Cell Carcinoma 2024
• The Journal of biological chemistry
  Rudd Justin C., Membrane structure and internalization dynamics of human Flower isoforms hFWE3 and hFWE4 indicate a conserved endocytic role for hFWE4, p. 104945 - 104945 2023
• Journal of clinical oncology
  Rana Ricky, Targeting Exportin 1 as treatment for cutaneous squamous cell carcinoma
  41:16_suppl, p. e21564 - e21564 2023
• The Journal of biological chemistry
  Rudd Justin, Abstract 1432: Structural determination and internalization dynamics of human Flower isoforms
  299:3, p. 103795 2023
• Biophysical journal
  Nichols Michael G., Impact of cell culture conditions on assessment of cellular metabolism in vitro by NAD(P)H phasor flim with application to in vivo diagnostic imaging for non-invasive biopsy
  121:3, p. 276a - 276a 2022
• Journal of biomedical optics
  Pham Dan L, Development and characterization of phasor-based analysis for FLIM to evaluate the metabolic and epigenetic impact of HER2 inhibition on Squamous Cell Carcinoma (SCC) cultures
  26:10 2021
• Journal of Biomedical Optics
  Pham Dan L., Development and characterization of phasor-based analysis for FLIM to evaluate the metabolic and epigenetic impact of HER2 inhibition on squamous cell carcinoma cultures
  26:10 2021
• Carcinogenesis
  Holmes Thomas R., Targeting 14-3-3ϵ activates apoptotic signaling to prevent cutaneous squamous cell carcinoma
  42:2, p. 232 - 242 2021
• Oncotarget
  Holmes Thomas R., Targeting 14-3-3ε-CDC25A interactions to trigger apoptotic cell death in skin cancer
  11:35, p. 3267 - 3278 2020
• Journal of Dermatological Science
  Lobl Marissa B., Targeted next-generation sequencing of matched localized and metastatic primary high-risk SCCs identifies driver and co-occurring mutations and novel therapeutic targets
  99:1, p. 30 - 43 2020
• Biophysical journal
  Nichols Michael G., Phasor-FLIM Quantification of Changes in Keratinocyte Metabolism and Tissue Architecture in a Longitudinal Study of UV-induced Skin Cancer
  118:3, p. 307a - 307a 2020
• Molecular Carcinogenesis
  Holmes Thomas R., Aberrant localization of signaling proteins in skin cancer
  58:9, p. 1631 - 1639 2019
• Molecular Carcinogenesis
  Al-Matouq Jenan, CDC25B and CDC25C overexpression in nonmelanoma skin cancer suppresses cell death
  58:9, p. 1691 - 1700 2019
• Nature
  Madan Esha, Flower isoforms promote competitive growth in cancer
  572:7768, p. 260 - 264 2019
• Biophysical journal
  Myers Dominick, Two-Photon Imaging of NADH in SKH1 Mice Reveals Changes in Keratinocyte Metabolism with Chronic UVA Exposure
  116:3, p. 281a - 282a 2019
• Cancer research (Chicago, Ill.)
  Holmes Thomas R., Abstract LB-190: CDC25A suppression of apoptosis in cutaneous squamous cell carcinoma depends on 14-3-3ϵ
  78:13_Supplement, p. LB-190 - LB-190 2018
• Journal of Biological Chemistry
  Madan Esha, The curcumin analog HO-3867 selectively kills cancer cells by converting mutant p53 protein to transcriptionally active wildtype p53
  293:12, p. 4262 - 4276 2018
• Cancer Letters
  Al-Matouq Jenan, Accumulation of cytoplasmic CDC25A in cutaneous squamous cell carcinoma leads to a dependency on CDC25A for cancer cell survival and tumor growth
  410, p. 41 - 49 2017
• Experimental Dermatology
  Bichsel Kyle J., The Epidermal Growth Factor Receptor Decreases Stathmin 1 and Triggers Catagen Entry in the Mouse
  25:4, p. 275 - 281 2016
• Molecular Carcinogenesis
  Rao Velidi H., Erbb2 up-regulation of ADAM12 expression accelerates skin cancer progression
  54:10, p. 1026 - 1036 2015
• Frontiers in Oncology
  Hammiller Brianna O., A Method for the Immortalization of Newborn Mouse Skin Keratinocytes
  5, p. (9 pages) 2015
• Journal of Dermatological Science
  Shirley Stephanie H., Role of the Epidermal Growth Factor Receptor in Ultraviolet Radiation Induction of Snail Family Transcription Factors
  76:2, p. 149 - 151 2014
• Cancer research (Chicago, Ill.)
  Almatouq Jenan, Abstract 1310: Increased cytoplasmic CDC25A phosphatase in cutaneous squamous cell carcinoma leads to 14-3-3 relocalization and suppression of apoptosis
  74:19_Supplement, p. 1310 - 1310 2014
• Molecular Carcinogenesis
  Rao Velidi H., Erbb2 up-regulation of ADAM12 expression accelerates skin cancer progression
  ePub ahead of print, p. 11 pages 2014
• PloS one
  Bichsel Kyle J., Role for the Epidermal Growth Factor Receptor in Chemotherapy-Induced Alopecia
  8:7, p. 1 - 12 2013
• ISRN Dermatology
  El-Abaseri Taghrid Bahig, The Epidermal Growth Factor Receptor Increases Cytokine Production and Cutaneous Inflammation in Response to Ultraviolet Irradiation
  2013, p. 1 - 11 2013
• Cancer research (Chicago, Ill.)
  Bichsel Kyle J., Abstract 1219: Defective catagen entry in EGFR deficient skin precedes cutaneous inflammation
  72:8_Supplement, p. 1219 - 1219 2012
• Carcinogenesis
  Yanagida J., Accelerated elimination of ultraviolet-induced DNA damage through apoptosis in CDC25A deficient skin
  33:9, p. 1754 - 1761 2012
• Oncogene
  Rao Velidi H., A positive feedback loop between HER2 and ADAM12 in human head and neck cancer cells increases migration and invasion
  31:23, p. 2888 - 2898 2012
• The FASEB journal
  Trotter Caitlyn, Evidence for critical period in development of cutaneous innervation: A study in nude mice
  25:S1, p. lb29 - lb29 2011
• Anatomical Record
  Maklad Adel, Development of innervation to maxillary whiskers in mice
  293:9, p. 1553 - 1567 2010
• Molecular Carcinogenesis
  Virador Victoria M., The human promyelocytic leukemia protein is a tumor suppressor for murine skin carcinogenesis
  48:7, p. 599 - 609 2009
• Molecular Carcinogenesis
  Virador Victoria M., The Human Promyelocytic Leukemia Protein Is a Tumor Suppressor for Murine Skin Carcinogenesis
  48:7, p. 599 - 609 2009
• American Journal of Pathology
  Madson Justin G., Erbb2 Suppresses DNA Damage-Induced Checkpoint Activation and UV-Induced Mouse Skin Tumorigenesis
  174:6, p. 2357 - 2366 2009
• Journal of Investigative Dermatology
  Maklad Adel, The EGFR Is Required for Proper Innervation to the Skin
  129:3, p. 690 - 698 2009
• Cell and Tissue Research
  Beisel Kirk W., Regenerating cochlear hair cells: quo vadis stem cell
  333:3, p. 373 - 379 2008
• Toxicologic pathology
  Lynch Dave, Mouse skin models for carcinogenic hazard identification
  35:7, p. 853 - 864 2007
• Molecular Carcinogenesis
  Madson J. G., Multiple mechanisms of Erbb2 action after ultraviolet irradiation of the skin
  46:8, p. 624 - 628 2007
• Pediatric Dermatology
  Hornung R. L., Skin cancer prevention in the primary care setting: assessment using a standardized patient
  24:2, p. 108 - 112 2007
• Toxicologic Pathology
  Lynch Dave, Mouse skin models for carcinogenic hazard identification: utilities and challenges
  35:7, p. 853 - 864 2007
• Journal of Biomedicine and Biotechnology
  El-Abaseri Taghrid B., EGFR activation and ultraviolet light-induced skin carcinogenesis, p. 97939 2007
• BioEssays
  Fritzsch Bernd, The molecular basis of neurosensory cell formation in ear development: a blueprint for hair cell and sensory neuron regeneration?
  28:12, p. 1181 - 1193 2006
• American Journal of Pathology
  Madson Justin G., Erbb2 regulates inflammation and proliferation in the skin after ultraviolet irradiation
  169:4, p. 1402 - 1414 2006
• Brain Research
  Morris Jacqueline K., A disorganized innervation of the inner ear persists in the absence of ErbB2
  1091:1, p. 186 - 199 2006
• Carcinogenesis
  El-Abaseri Taghrid B., Ultraviolet irradiation induces keratinocyte proliferation and epidermal hyperplasia through the activation of the epidermal growth factor receptor
  27:2, p. 225 - 231 2006
• Journal of Investigative Dermatology
  Khan Gausal A., Harvey-ras gene expression and epidermal cell proliferation in dibenzo[a,I]pyrene-treated early preneoplastic SENCAR mouse skin
  125:3, p. 567 - 574 2005
• Lung cancer (Amsterdam, Netherlands)
  Jensen R., P-057 Expression of the cyclin-dependent kinase inhibitor p21 is linkedto regulation of RAD51 in response to etoposide treatment of small cell lung cancer cells
  49, p. S129 - S129 2005
• Cancer Research
  El-Abaseri Taghrid B., Chemoprevention of UV light-induced skin tumorigenesis by inhibition of the epidermal growth factor receptor.
  65:9, p. 3958 - 3965 2005
• Toxicologic pathology
  Fuhrman Jill, Mechanisms of SEPA 0009-induced tumorigenesis in v-rasHa transgenic Tg.AC mice.
  33:6, p. 623 - 630 2005
• Journal of Investigative Dermatology
  Repertinger Susan K., EGFR enhances early healing after cutaneous incisional wounding
  123:5, p. 982 - 989 2004
• Pharmacotherapy
  Snella Kathleen A., Pharmacist Compensation for Cognitive Services: Focus on the Physician Office and Community Pharmacy
  24:3, p. 372 - 388 2004
• Journal of Biological Chemistry
  Wei Sung Jen, 12-O-Tetradecanoylphorbol-13-acetate and UV Radiation-induced Nucleoside Diphosphate Protein Kinase B Mediates Neoplastic Transformation of Epidermal Cells
  279:7, p. 5993 - 6004 2004
• Cell and Tissue Research
  Maklad Adel, Innervation of the maxillary vibrissae in mice as revealed by anterograde and retrograde tract tracing
  315:2, p. 167 - 180 2004
• Cancer Research
  Hansen Laura A., A PMLRARA transgene results in a retinoid-deficient phenotype associated with enhanced susceptibility to skin tumorigenesis
  63:17, p. 5257 - 5265 2003
• Cancer Research
  Hansen Laura A., A PMLRARA transgene results in a retinoid-deficient phenotype associated with enhanced susceptibility to skin tumorigenesis
  63:17, p. 5257 - 5265 2003
• Oncogene
  Seker Hasan, UV-C-induced DNA damage leads to p53-dependent nuclear trafficking of PML
  22:11, p. 1620 - 1628 2003
• Cancer Research
  Woodworth Craig D., Targeted disruption of the epidermal growth factor receptor inhibits development of papillomas and carcinomas from human papillomavirus-immortalized keratinocytes
  60:16, p. 4397 - 4402 2000
• Cancer research
  Hansen L A, The epidermal growth factor receptor is required to maintain the proliferative population in the basal compartment of epidermal tumors
  60:13, p. 3328 - 3332 2000
• Cancer Research
  Hansen Laura A., The epidermal growth factor receptor is required to maintain the proliferative population in the basal compartment of epidermal tumors
  60:13, p. 3328 - 3332 2000
• Carcinogenesis
  Hansen Laura A., Retinoids in chemoprevention and differentiation therapy
  21:7, p. 1271 - 1279 2000
• Carcinogenesis
  Hansen Laura A., Effect of the viable-yellow (A(vy)) agouti allele on skin tumorigenesis and humoral hypercalcemia in v-Ha-ras transgenic TG.AC mice
  19:10, p. 1837 - 1845 1998
• Experimental Cell Research
  Saitoh Atsushi, Characterization of Wnt gene expression in murine skin
  243:1, p. 150 - 160 1998
• Genes and Development
  Robles Ana I., Reduced skin tumor development in cyclin D1-deficient mice highlights the oncogenic ras pathway in vivo
  12:16, p. 2469 - 2474 1998
• Cancer Research
  Tennenbaum Tamar, Topical retinoic acid reduces skin papilloma formation but resistant papillomas are at high risk for malignant conversion
  58:7, p. 1435 - 1443 1998
• Toxicologic pathology
  Humble Michael C., TGFα is dispensable for skin tumorigenesis in Tg.AC mice
  26:4, p. 562 - 569 1998
• Cancer Research
  Diugosz Andrzej A., Targeted disruption of the epidermal growth factor receptor impairs growth of squamous papillomas expressing the v-ras(Ha) oncogene but does not block in vitro keratinocyte responses to oncogenic ras
  57:15, p. 3180 - 3188 1997
• American Journal of Pathology
  Hansen Laura A., Genetically null mice reveal a central role for epidermal growth factor receptor in the differentiation of the hair follicle and normal hair development
  150:6, p. 1959 - 1975 1997
• Carcinogenesis
  Hansen Laura A., Association of tumor development with increased cellular proliferation and transgene overexpression, but not c-Ha-ras mutations, in v-Ha-ras transgenic Tg.AC mice
  17:9, p. 1825 - 1833 1996
• Archives of Oral Biology
  Wright J. T., Odontogenic tumours in the v-Ha-ras (TG · AC) transgenic mouse
  40:7, p. 631 - 638 1995
• Science
  Threadgill David W., Targeted disruption of mouse EGF receptor
  269:5221, p. 230 - 234 1995
• Progress in clinical and biological research
  Hansen L. A., A transgenic mouse model (TG.AC) for skin carcinogenesis
  391, p. 223 - 235 1995
• Molecular Carcinogenesis
  French John E., Cytogenetic analysis of malignant skin tumors induced in chemically treated TG.AC transgenic mice
  11:4, p. 215 - 226 1994
• Proceedings of the National Academy of Sciences of the United States of America
  Hansen Laura A., Follicular origin of epidermal papillomas in v-Ha-ras transgenic TG.AC mouse skin
  91:16, p. 7822 - 7826 1994
• Mutagenesis
  Tennant Raymond W., Gene manipulation and genetic toxicology
  9:3, p. 171 - 174 1994
• Molecular Carcinogenesis
  Hansen Laura A., Focal transgene expression associated with papilloma development in v‐Ha‐ras–transgenic TG.AC mice
  9:3, p. 143 - 154 1994
• Cancer genetics and cytogenetics
  Libbus Bisharah L., Highly repetitive chromosome changes associated with skin tumor development in transgenic mice treated with TPA
  66:2, p. 152 - 152 1993
• Breast cancer research and treatment
  SPANG-THOMSEN M, Growth kinetics of four human breast carcinomas grown in nude mice
  14:2, p. 235 - 243 1989
• Cancer Research
  Smart Robert C., Synthetic Lipid Second Messenger sn-1,2-Didecanoylglycerol
  49:16, p. 4455 - 4458 1989
• Water, Air, and Soil Pollution
  Hansen Laura A., A method for chemical fractionation of chloride from complex effluents
  42:3-4, p. 259 - 265 1988

Presentations

• Society for Investigative Dermatology Annual Meeting 2020
• MSBRF poster presentation, Flower isoforms regulate keratinocyte differentiation during cutaneous squamous cell carcinoma development. Justin Rudd, Kelsey Novak, Matti Holmes, Kelsey Hulen, Laura Hansen 2020
• EFFECTS OF ES1P3 AND ZF47-88 ON CELL VIABILITY OF SCC12.B2 AND SCC13 CELLS Ryan O'Gara, Thomas R. Holmes, Kelsey Hulen, Sándor Lovas, Laura A. Hansen Midwest Student Biomedical Research Forum, 2020 2020
• 1. Two-photon imaging of NADH in SKH1 mice reveals changes in keratinocyte metabolism with chronic UVA exposure. Dominick Myers, Katie D. Sotelo, Dan L. Che, Marifel F. Gabriel, Ben G. Huerter, Kelsey A. Jackson, Molly Myers, Duyen Nguyen, Brooke L. Yang, Laura A. Hansen, Michael G. Nichols, 83rd Annual Meeting of the Biophysical Society, Baltimore Maryland, March 2019 2019
• Sarah C. Gwazdacz, Sarah L. Schilchte, Matti Holmes, Natasha Sioda, Matthew C. Zimmerman, Gary Madsen, and Laura A. Hansen. The delivery and use of Pro-NPTM in the reduction of UV-induced oxygen radicals in skin. Midwest Student Biomedical Research Forum, March 2019. 2019
• Natasha Sioda, Tommy Holmes, Sarah Gwazdacz, Matti Homes, and Laura A. Hansen. Targeting 14-3-3 decreases anti-apoptotic signaling in squamous cell carcinoma in vivo. Midwest Student Biomedical Research Forum, March 2019. 2019
• Megan Machek, Matti Holmes, Caleb Freeman, Zhao-Yi Wang, Laura A. Hansen. Treatment of squamous cell carcinoma using ER-a36 targeted drug icaritin. Midwest Student Biomedical Research Forum, March 2019. 2019
• Sandor Lovas, Thomas Holmes, Nicholas Y. Palermo, and Laura A. Hansen. Developing pepetide analogs for skin cancer treatment. International Peptide Conference, 2019. 2019
• Invited Speaker, Title: Targeting CDC25A and 14-3-3e interactions in nonmelanoma skin cancer, International Investigative Skin Carcinogenesis Conference, Austin TX, October, 2018. 2018
• Targeting of estrogen receptor-α36 suppresses growth of cutaneous squamous cell carcinoma, Caleb Freeman, Matti Holmes, Zhao-Yi Wang, and Laura A. Hansen International Investigational Skin Carcinogenesis Conference, Orlando, Florida 2018
• Invited Speaker, Title: CDC25 and 14-3-3 in UV-induced skin cancer progression, American Society for Photobiology annual meeting 2018
• Targeting CDC25A suppression of apoptosis in cutaneous squamous cell carcinoma depends on 14-3-3e, Thomas R. Holmes and Laura A. Hansen, American Association for Cancer Research annual meeting, Chicago, IL 2018
• Flower Proteins and Cell Competition in Skin Cancer Kimberly M. Fazio, Nicholas Tran, Matti Holmes, Ekaterina Halivelakis, Celena Derderian, Justin G. Madson, Rajan Gogna, Laura A. Hansen, MSBRF 2018
• ESTROGEN RECEPTOR-a36 TARGETING BY ICARITIN RESTRICTS IN VIVO GROWTH OF SQUAMOUS CELL CARCINOMA IN XENOGRAFT BY INCREASING DIFFERENTIATION, DECREASING PROLIFERATION, AND REDUCING THE CANCER STEM CELL POPULATION, S. Caleb Freeman, Matti Holmes, Nicholas Tran, Kimberly Fazio, Zhao-Yi Wang2, Laura A. Hansen, MSBRF 2018
• TARGETING OF ESTROGEN RECEPTOR-α36 DECREASES SKIN CANCER STEM CELL NUMBERS AND SUPPRESSES SKIN CANCER GROWTH, Matti Holmes1\, Caleb Freeman, Dan Pham, Tommy R. Holmes, Tammy Wang, Zhao-Yi Wang, Laura A. Hansen, MSBRF 2018
• Invited Speaker, Title: Novel Targets for Skin Carcinogenesis, LB595 Cancer and Smoking-related Diseases Program 2017
• Invited Speaker, Title: Estrogen Receptor alpha 36 in skin cancer progression 2017
• Presentation of research for LB595 site visit 2017
• Invited speaker, Title: Relocalized CDC25A suppresses cell death in cutaneous squamous cell carcinoma, The 12th International Skin Carcinogenesis Conference. 2017
• Invited Speaker, Title: Mechanisms of skin cancer development and progression, Department of Pharmacology, CUSOM 2016
• Seminar, Role of CDC25C phosphatase in non-melanoma skin cancer, LB595 2015
• Cassidy Plunkett, Brianna Hammiller, Kyle Bichsel, Jessica Gaulter, and Laura A. Hansen Epidermal growth factor receptor regulation of Stathmin 1 in mouse skin cancer, Creighton University Honors Day 2015
• Timothy Malouff, Kyle J. Bichsel, Yanhua Li, Brianna Hammiller, Carol Trempus, Laura A. Hansen EGFR AND STATHMIN1 IN PROGRESSION THROUGH THE HAIR CYCLE Midwest Student Biomedical Research Forum, 2015 *Third place poster presentation. 2015
• Lauren Nicola; Nicholas Tran; Jenan Al-Matouq; Brianna Hammiller; and Laura A. Hansen CYTOPLASMIC LOCALIZATION OF 14-3-3 IS ASSOCIATED WITH SUPPRESSION OF CELL DEATH IN CUTANEOUS SQUAMOUS CELL CARCINOMA Midwest Student Biomedical Research Forum 2015
• Invited Speaker, Title: HER2-regulated signaling in squamous cell carcinoma: 14-3-3 and CDC25, CU Department of Biomedical Sciences, 2014
• Invited Speaker, Title: HER2-regulated signaling in squamous cell carcinoma: ADAM12 and CDC25 phosphatases, Kansas State University 2014
• Al-Matouq, J.A., Ho, K.A., and Hansen, L.A. Increased cytoplasmic CDC25A phosphatases in cutaneous cquamous cell carcinoma leads to 14-3-3epsilon relocalization and suppression of apoptosis. Presentation at the American Association for Cancer Research Meeting, May 2014 2014
• Hansen, L.A. Novel biomarkers and therapeutic targets for nonmelanoma skin cancer. Oral presentation for LB595, April 2014 2014
• Al-Matouq, J.A., Ho, K.A., and Hansen, L.A. Increased cytoplasmic CDC25A phosphatases in cutaneous cquamous cell carcinoma leads to 14-3-3epsilon relocalization and suppression of apoptosis. Poster presentation at the Midwest Biomedical Student Research Forum, February, 2014 2014
• Platform presentation at the Society of Toxicology annual meeting in Baltimore MD 2009
• Invited speaker at Pennsylvania State University, College Station, PA 2008
• Invited seminar at UNL, Epidermal growth factor receptor: surprises from the skin 2008
• Invited speaker, VA, Omaha, NE 2008
• Erbb2 and ultraviolet irradiation in skin carcinogenesis, University of Nebraska, Lincoln, NE 2006
• Inhibition of erbB2 suppresses UV-induced skin tumorigenesis through a mechanism independent of EGFR, American Association for Cancer Research 2006
• The role of Erbb2 in the response of the skin to UV, Nebraska Center for Cellular Signaling 2006
• Seminar title: The role of erbB2 in UV-induced skin carcinogenesis. 2005
• Seminar title: EGFR in cutaneous innervation 2004
• EGFR in peripheral nervous system innervation 2004
• The epidermal growth factor receptor in cancer biology 2003
• Invited speaker, Growth factor receptors, sunlight, and skin cancer, National Institute for Environmental Health Sciences, Research Triangle Park, NC 2003
• Invited speaker at the Great Plains States Society for Molecular Biology and Genetics annual meeting 2003
• Invited speaker, 4th Annual Steve Schiff Center for Skin Cancer Research Symposium, Title: The epidermal growth factor receptor regulates cell cycling and cell death during skin carcinogenesis 2002
• Invited speaker, VA hospital, Title: The epidermal growth factor receptor regulates cell death and division during skin carcinogenesis 2001
• Invited speaker, 3rd Midwest Regional AAAS Meeting, Title: Regulation of cell growth and death by the epidermal growth factor receptor during skin carcinogenesis 2001
• Invited speaker, Department of Pharmacology Seminar Series, UNMC, Title: Regulation of cutaneous cell division and cell death by the epidermal growth factor receptor 2001
• Panel discussion member, National Institute for Environmental Health Sciences Science Forum Topic: Searching for Faculty Positions, A Discussion by TIP Grantees 2001
• A PMLRARalpha transgene results in a retinoid-deficient phenotype associated with enhanced susceptibility to skin tumorigenesis, poster presentation at the American Association for Cancer Research annual meeting 2001
• UNMC Department of Cell Biology, seminar, Title: Epidermal growth factor receptor mediated maintenance of cell proliferation in skin tumorigenesis. 2001
• 3/5/2001 UNMC Department of Biochemistry, seminar, Regulation of cell division and differentiation by the epidermal growth factor receptor in the skin. 2001

Federal

• INBRE
  PI: M. Nichols (Co-I: Hansen)
  Title: Metabolic imaging of disease progression in skin cancer by FLIM

• NIH RO1 ES015585
  Title: Mechanisms of UV-induced skin carcinogenesis

• NIH ARRA
  Title: Summer student supplement to RO1

• NIH Center of Biomedical Research Excellence (COBRE) (PI: Wheelock) Project PI 50% effort
  My project title: erbB2 in UV-induced skin carcinogenesis
  National Institutes of Health
  Award: $686,821 direct costs for my portion, $276,599 indirect (total award approximately $10,000,000 over five years)

• NIH RO1 (PI: Kusewitt) Collaborating investigator
  Title: Modulators of EMT in skin carcinogenesis

• NIH COBRE (PI: Smith) Project Principal Investigator 40% effort
  Title: The molecular biology of neurosensory development (My individual project title is “The role of EGFR in sensory development.)

• NIH K-22 Award ES00365-01
  Title: The role of EGFR in UV-induced skin carcinogenesis

Industry/Corporation

• ProTransit Nanotherapy Project
  Title: The Protective Efficacy of PLGA Nanoparticles Encapsulating Antioxidant Enzymes against UV Radiation Exposure

• Connetics Corporation
  Title: Mechanisms of tumorigenesis in Tg.AC mice

• Connetics Corporation
  Title: Analysis of the effects of topically applied agents to Tg.AC skin

• Macrochem Corporation
  Title: Mechanisms of SEPA-induced carcinogenesis in Tg.AC mice

State

• State of NE-LB506

• State of NE-LB595
  Title: Molecular and cellular mechanisms of carcinogenesis program

• State of NE-LB595
  Title: Cancer and smoking-related diseases seminar series

• NE-LB595 Pilot Project
  Title: ADAM12 and head and neck cancer progression

• NE-LB595 Pilot Project
  Title: Oral carcinogenesis and ADAM12

• State of NE-LB506
  Title: HER2 and the response to chemotherapeutic agents in SCC

• State of NE-LB692
  Title: Does defective catagen entry trigger folliculitis in Egfr mutant skin?

• State of NE-LB595
  Title: Mechanisms of cell cycle regulation by Erbb2

• State of NE-LB692
  Title: The role of erbB2 in PNS, skin, and ear as revealed by conditional mutation analysis

Foundation/Association

• The Dobleman Institute for Head and Neck Cancer Research
  
  Title: Matching funds for ADAM12 and head and neck cancer progression

• Health Future Foundation Scholar Award
  Title: Regulation of cell cycle progression by HER2 in mammary cancer cells

Other

• CURAS Project
  Title: Cytoplasmic CDC25A localization and suppression of apoptosis in cancer cells.

Awards

• Dr. Robert Heaney Graduate Research Mentor Award
  Creighton University
• 1st place Graduate Student Platform Presentation by student Justin Rudd
  1st place Graduate Student Platform Presentation by student Justin Rudd in Basic Sciences during University Research Week
• University Research Award
  Creighton University
• First Place Prize for Graduate Student Poster
  Awarded to my advisee Matti Holmes for her research performed in my lab
  Creighton University Research Day
• Third place prive for poster presentation by medical student and mentee Timothy Malouff at the Midwest Biomedical Student Research Forum
  Third place prive for poster presentation by medical student and mentee Timothy Malouff at the Midwest Biomedical Student Research Forum
• Third place poster awarded to my Ph.D. student Justin Madson at the Midwest Biomedical Student Research Forum
  Third place poster awarded to my Ph.D. student Justin Madson at the Midwest Biomedical Student Research Forum
• Society of Investigative Dermatology Eugene M. Farber Endowment Award
  Society of Investigative Dermatology Eugene M. Farber Endowment Award

Consulting

• Protransit Nanotherapy, LLC External Advisory Board
  Board Member
  Protransit Nanotherapy
  2015 - 2015