Medical Microbiology and Immunology (Master of Science)
Graduate School
CRISS I - Criss 1 - 520
Nancy Dohse Hanson, PhD
Professor
Medical Microbiology and Immunology
Examples of the most recent publications can be found at this PubMed link.
Research Focus
Our laboratory focuses on many aspects of antibiotic resistance and the pathogenesis of urinary tract infections caused by E. coli. Our research explores the molecular mechanisms of antibiotic resistance, both chromosomal and plasmid-mediated, in gram-negative pathogens such as Escherichia coli, Klebsiella pneumoniae, Salmonella spp., and Pseudomonas aeruginosa. Specifically, we are interested in the identification of selective pressures required for the emergence of resistance, the regulation of gene and protein expression involved in resistant phenotypes, and metabolic pathways required for both pathogenesis and antibiotic tolerance in Enterobacterales. In addition, we are interested in the development of diagnostic assays to detect not only the phenotype of organisms resistant to antibiotics but the mechanisms by which the organism becomes resistant.
Multidrug Resistance A Global Concern Khalaf N. G., The Scope of Bacterial Resistance to Antibiotics in some Countries in the Middle East and North Africa [Book Chapter] 2012
Articles
Torres María P., A multiplex real-time PCR assay for identification of multi-drug resistant Gram-negative pathogens 2016
Publications
The Journal of infectious diseases Maclean Alyssa K W, What Contributes to the MIC? Beyond β-Lactamase Gene Detection in Klebsiella pneumoniae 2024
Maclean Alyssa K.W., Intrapatient transfer of an uncommon carbapenemase in Nebraska 2022
Mack Andrew R., A standard numbering scheme for class c β-lactamases 2021
Journal of Antimicrobial Chemotherapy Suelter Corey S., OmpC regulation differs between ST131 and non-ST131 Escherichia coli clinical isolates and involves differential expression of the small RNA MicC 75:5, p. 1151 - 1158 2020
Antimicrobial agents and chemotherapy Mack Andrew R., A standard numbering scheme for class C β-lactamases 64:3 2020
MicrobiologyOpen Harrison Lucas B., lptG contributes to changes in membrane permeability and the emergence of multidrug hypersusceptibility in a cystic fibrosis isolate of Pseudomonas aeruginosa 8:11 2019
Microbiology Resource Announcements Harrison Lucas B., Draft genome assemblies of clinical isolates of klebsiella pneumoniae V9011662 and enterobacter hormaechei Entb306 8:15 2019
Genome Announcements Harrison Lucas B., Draft genome sequence of the mucoid Pseudomonas aeruginosa clinical isolate PA34 5:46 2017
Antimicrobial Agents and Chemotherapy Harrison Lucas, High Resolution Melting Analysis for the Rapid Detection of Sequence Type 131 Escherichia Coli 61:6 2017
Diagnostic Microbiology and Infectious Disease Bork Jacqueline T., Impact of CLSI and EUCAST Cefepime breakpoint changes on the susceptibility reporting for Enterobacteriaceae 2017
BioTechniques Connelly Christopher M., Plasmid-mediated β-lactamases 61:5, p. 272 - 275 2016
Antimicrobial Agents and Chemotherapy Dixon Nyssa, IMP-27, a Unique Metallo-Beta-Lactamase Identified in Geographically Distinct Isolates of Proteus Mirabilis 60:10, p. 6418 - 6421 2016
Antimicrobial Agents and Chemotherapy Furuyama T., Structural and Mutagenic Analysis of Metallo-Beta-Lactamase IMP-18 60:9, p. 5521 - 5526 2016
The Journal of Antimicrobial Chemotherapy Geyer Chelsie N., Evaluation of CTX-M steady-state mRNA, mRNA half-life and protein production in various STs of Escherichia coli 71:3, p. 607 - 616 2016
Microbiologyopen Fowler Randal C., The OpdQ porin of Pseudomonas aeruginosa is regulated by environmental signals associated with cystic fibrosis including nitrate-induced regulation involving the NarXL two-component system 4:6, p. 967 - 982 2015
Journal of Clinical Microbiology Ledeboer N. A., Identification of Gram-Negative Bacteria and Genetic Resistance Determinants from Positive Blood Culture Broths using the Verigene Gram-Negative Blood Culture Multiplex Microarray-Based Molecular Assay 53:8, p. 2460 - 2472 2015
Biotechniques Connelly C. M., Antibiotic Resistance Monitoring and Detection (Arm-d™) Pcr Kits: Arm-d™ for β-Lactamase Id – Technical Note: Detection of Esbls, Mbls, Kpcs, and Plasmid-Mediated Ampcs, using the β-Lactamase Id Kit to Identify Antibiotic Resistance in Gram-Negative Patho 57:6, p. 317 - 318 2014
BioTechniques Connelly Christopher M., Philisa® ampC ID Kit – Technical Note 57:4, p. 214 - 215 2014
Journal of Clinical Microbiology Geyer Chelsie N., Multiplex high-resolution melting analysis as a diagnostic tool for detection of plasmid-mediated AmpC ??-lactamase genes 52:4, p. 1262 - 1265 2014
PLoS One Fowler Randal C., Emergence of Carbapenem Resistance Due to the Novel Insertion Sequence ISPa8 in Pseudomonas aeruginosa 9:3, p. e91299 2014
Diagnostic microbiology and infectious disease Fowler Randal C., Whole Genome Mapping of the First Reported Case of KPC-2-positive Klebsiella pneumoniae ST258 in Nebraska 79:3, p. 384 - 386 2014
Journal of Antimicrobial Chemotherapy Roth Amanda L., Effect of drug treatment options on the mobility and expression of blaKPC 68:12, p. 2779 - 2785 2013
Acta Crystallographica Section F: Structural Biology and Crystallization Communications Furuyama Takamitsu, Purification, crystallization and preliminary X-ray analysis of IMP-18, a class B carbapenemase from Pseudomonas aeruginosa 69:12, p. 1397 - 1400 2013
Biotechniques Geyer Chelsie N., Rapid Screening of Transformants using the Streck Philisa® Thermal Cycler 55:5, p. 274 2013
Hanson Nancy D., Resistance in Gram-negative Pathogens 2013
PLoS pathogens Hu Guoku, Release of Luminal Exosomes Contributes to TLR4-Mediated Epithelial Antimicrobial Defense 9:4 2013
Diagnostic Microbiology and Infectious Disease Geyer Chelsie N., Rapid PCR amplification protocols decrease the turn-around time for detection of antibiotic resistance genes in Gram-negative pathogens 77:2, p. 113 - 117 2013
Journal of Clinical Microbiology Roth A. L., Rapid Detection and Statistical Differentiation of KPC Gene Variants in Gram-negative Pathogens Using High Resolution Melting and ScreenClust Analysis 51:1, p. 61 - 65 2013
Journal of clinical microbiology Geyer Chelsie N., Development of a TaqMan multiplex PCR assay for detection of plasmid-mediated AmpC β-lactamase genes 50:11, p. 3722 - 3725 2012
Antimicrobial agents and chemotherapy Johnson James R., Molecular epidemiological analysis of Escherichia coli sequence type ST131 (O25:H4) and bla CTX-M-15among extended-spectrum-β- lactamase-producing E. coli from the United States, 2000 to 2009 56:5, p. 2364 - 2370 2012
Journal of Antimicrobial Chemotherapy Kurpiel Philip M., Point mutations in the inc antisense RNA gene are associated with increased plasmid copy number, expression of blaCMY-2 and resistance to piperacillin/tazobactam in Escherichia coli 67:2, p. 339 - 345 2012
Journal of Clinical Microbiology Roth A. L., Production of KPC-2 Alone Does Not Always Result in Resistant beta-lactam MICs in Gram-negative Pathogens 50:12, p. 4183 - 4184 2012
Epidemiology research international Robledo Iraida E., Dissemination and Molecular Epidemiology of KPC-Producing Klebsiella pneumoniae Collected in Puerto Rico Medical Center Hospitals during a 1-Year Period 2011, p. 1 - 8 2011
Clinical Neurophysiology Powell D., Enhancement of parkinsonian rigidity with contralateral hand activation 122:8, p. 1595 - 1601 2011
Antimicrobial Agents and Chemotherapy Roth Amanda L., blaKPC RNA Expression Correlates with Two Transcriptional Start Sites but Not Always with Gene Copy Number in Four Genera of Gram-negative Pathogens 55:8, p. 3936 - 3938 2011
Journal of Antimicrobial Chemotherapy Kurpiel Philip M., Association of IS5 with divergent tandem blaCMY-2 genes in clinical isolates of Escherichia coli 66:8, p. 1734 - 1738 2011
Antimicrobial agents and chemotherapy Borgianni Luisa, Genetic context and biochemical characterization of the IMP-18 metallo-β-lactamase identified in a Pseudomonas aeruginosa isolate from the United States 55:1, p. 140 - 145 2011
Microbe Hanson Nancy D., Molecular diagnostics could help in coping with hidden β-lactamases 5:8, p. 333 - 339 2010
Munier G. K., Positive extended-spectrum-β-lactamase (ESBL) screening results may be due to AmpC β-lactamases more often than to ESBLs 2010
AbdelGhani Sameh M.M., First report of CTX-M-14 -producing clinical isolates of Salmonella serovar Typhimurium from Egypt 2010
Clinical Microbiology Reviews Lister Philip D., Antibacterial-resistant Pseudomonas aeruginosa: clinical impact and complex regulation of chromosomally encoded resistance mechanisms 22:4, p. 582 - 610 2009
Journal of Antimicrobial Chemotherapy Wolter Daniel J., Multiple genotypic changes in hypersusceptible strains of Pseudomonas aeruginosa isolated from cystic fibrosis patients do not always correlate with the phenotype 64:2, p. 294 - 300 2009
BMC Infectious Diseases Khalaf Noha G., Characterization of CTX-M ESBLs in Enterobacter cloacae, Escherichia coli and Klebsiella pneumoniae clinical isolates from Cairo, Egypt 9 2009
Antimicrobial Agents and Chemotherapy Wolter Daniel J., Surveillance of Carbapenem-Resistant Pseudomonas aeruginosa Isolates from Puerto Rican Medical Center Hospitals: Dissemination of KPC and IMP-18 beta-Lactamases 53:4, p. 1660 - 1664 2009
Antimicrobial agents and chemotherapy Wolter Daniel J., Phenotypic and enzymatic comparative analysis of the novel KPC variant KPC-5 and its evolutionary variants, KPC-2 and KPC-4 53:2, p. 557 - 562 2009
Antimicrobial Agents and Chemotherapy Schmidtke Amber J., Role of ampD Homologs in Overproduction of AmpC in Clinical Isolates of Pseudomonas aeruginosa 52:11, p. 3922 - 3927 2008
Antimicrobial Agents and Chemotherapy Hanson Nancy D., Surveillance of community-based reservoirs reveals the presence of CTX-M, imported AmpC, and OXA-30 beta-lactamases in urine isolates of Klebsiella pneumoniae and Escherichia coli in a US community 52:10, p. 3814 - 3816 2008
Clinical Infectious Diseases Wolter Daniel J., Emergence of Carbapenem Resistance in Pseudomonas aeruginosa Isolates from a Patient with Cystic Fibrosis in the Absence of Carbapenem Therapy 46:12, p. e137 - e141 2008
Antimicrobial agents and chemotherapy Wolter Daniel J., Increased expression of ampC in Pseudomonas aeruginosa mutants selected with ciprofloxacin 51:8, p. 2997 - 3000 2007
Diagnostic Microbiology and Infectious Disease Netzel Tisha C., The AmpC inhibitor, Syn2190, can be used to reveal extended-spectrum β-lactamases in Escherichia coli 58:3, p. 345 - 348 2007
Antimicrobial Agents and Chemotherapy Hong S. G., In vitro studies with DQ-113 and comparison fluoroquinolones to determine propensities to select resistance in gram-positive cocci 51:4, p. 1512 - 1514 2007
Journal of Medical Microbiology Sidjabat Hanna E., Identification of plasmid-mediated extended-spectrum and AmpC β-lactamases in Enterobacter spp. isolated from dogs 56:3, p. 426 - 434 2007
Moland Ellen Smith, Klebsiella pneumoniae isolate producing at least eight different β-lactamases, including AmpC and KPC β-lactamases [1] 2007
Journal of Antimicrobial Chemotherapy Wickman P. A., In vitro development of resistance to DX-619 and other quinolones in enterococci 58:6, p. 1268 - 1273 2006
Journal of Clinical Microbiology Moland E. S., Prevalence of newer beta-lactamases in gram-negative clinical isolates collected in the United States from 2001 to 2002 44:9, p. 3318 - 3324 2006
Journal of Medical Microbiology Sidjabat Hanna E., Emergence and spread of two distinct clonal groups of multidrug-resistant Escherichia coli in a veterinary teaching hospital in Australia 55:8, p. 1125 - 1134 2006
Antimicrobial Agents and Chemotherapy Schmidtke A. J., Model system to evaluate the effect of ampD mutations on AmpC-mediated beta-lactam resistance 50:6, p. 2030 - 2037 2006
Hanson Nancy D., First occurrence of a Pseudomonas aeruginosa isolate in the United States producing an IMP metallo-β-lactamase, IMP-18 [3] 2006
Journal of Antimicrobial Chemotherapy Sidjabat Hanna E., Identification of blaCMY-7 and associated plasmid-mediated resistance genes in multidrug-resistant Escherichia coli isolated from dogs at a veterinary teaching hospital in Australia 57:5, p. 840 - 848 2006
Antimicrobial Agents and Chemotherapy Wolter D. J., AmpC and OprD are not involved in the mechanism of imipenem hypersusceptibility among Pseudomonas aeruginosa isolates overexpressing the mexCD-oprJ efflux pump 49:11, p. 4763 - 4766 2005
Journal of Clinical Microbiology Song W., Failure of cefepime therapy in treatment of Klebsiella pneumoniae bacteremia 43:9, p. 4891 - 4894 2005
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America Hong Tao, Escherichia coli 40:10, p. e84 - 86 2005
Mortensen Joel E., New quality control strain for use in routine testing for production of extended-spectrum beta-lactamases by Enterobacteriaceae [1] 2005
Journal of clinical microbiology Pitout Johann D.D., Phenotypic and molecular detection of CTX-M-β-lactamases produced by Escherichia coli and Klebsiella spp. 42:12, p. 5715 - 5721 2004
Antimicrobial Agents and Chemotherapy Reisbig Mark D., Promoter sequences necessary for high-level expression of the plasmid-associated ampC beta-lactamase gene bla(MIR-1) 48:11, p. 4177 - 4182 2004
Antimicrobial Agents and Chemotherapy Hossain Ashfaque, Plasmid-mediated carbapenem-hydrolyzing enzyme KPC-2 in an Enterobacter sp. 48:11, p. 4438 - 4440 2004
Antimicrobial Agents and Chemotherapy Abdalhamid Baha, Community-onset disease caused by Citrobacter freundii producing a novel CTX-M beta-lactamase, CTX-M-30, in Canada 48:11, p. 4435 - 4437 2004
Journal of clinical microbiology Liebana Ernesto, Pediatric infection due to multiresistant Salmonella enterica serotype infantis in Honduras 42:10, p. 4885 - 4888 2004
Diagnostic Microbiology and Infectious Disease Wolter Daniel J., Multidrug resistance associated with mexXY expression in clinical isolates of Pseudomonas aeruginosa from a Texas hospital 50:1, p. 43 - 50 2004
FEMS Microbiology Letters Wolter Daniel J., Insertional inactivation of oprD in clinical isolates of Pseudomonas aeruginosa leading to carbapenem resistance 236:1, p. 137 - 143 2004
Clinical Infectious Diseases Pitout Johann D.D., Population-based laboratory surveillance for Escherichia coli-producing extended-spectrum β-Lactamases 38:12, p. 1736 - 1741 2004
Journal of Antimicrobial Chemotherapy Hossain Ashfaque, Plasmid-encoded functions compensate for the biological cost of AmpC overexpression in a clinical isolate of Salmonella typhimurium 53:6, p. 964 - 970 2004
Microbial Drug Resistance Liebana Ernesto, Characterization of β-Lactamases Responsible for Resistance to Extended-Spectrum Cephalosporins in Escherichia coli and Salmonella enterica Strains from Food-Producing Animals in the United Kingdom 10:1, p. 1 - 9 2004
Journal of clinical microbiology Pitout Johann D.D., Association between handling of pet treats and infection with Salmonella enterica serotype Newport expressing the AmpC β-lactamase, CMY-2 41:10, p. 4578 - 4582 2003
Journal of clinical microbiology Pitout J. D.D., Modification of the double-disk test for detection of Enterobacteriaceae producing extended-spectrum and AmpC β-lactamases 41:8, p. 3933 - 3935 2003
Journal of Antimicrobial Chemotherapy Hanson Nancy D., AmpC β-lactamases 52:1, p. 2 - 4 2003
Moland E. Smith, Discovery of CTX-M-like extended-spectrum β-lactamases in Escherichia coli isolates from five U.S. States [2] 2003
Journal of Antimicrobial Chemotherapy Reisbig Mark D., Factors influencing gene expression and resistance for Gram-negative organisms expressing plasmid-encoded ampC genes of Enterobacter origin 51:5, p. 1141 - 1151 2003
Journal of Antimicrobial Chemotherapy Mahlen Steven D., Analyses of ampC gene expression in Serratia marcescens reveal new regulatory properties 51:4, p. 791 - 802 2003
Journal of Antimicrobial Chemotherapy Moland Ellen Smith, Plasmid-mediated, carbapenem-hydrolysing β-lactamase, KPC-2, in Klebsiella pneumoniae isolates 51:3, p. 711 - 714 2003
Journal of clinical microbiology Coudron Philip E., Occurrence of extended-spectrum and ampC beta-lactamases in bloodstream isolates of Klebsiella pneumoniae 41:2, p. 772 - 777 2003
Antimicrobial agents and chemotherapy Moland Ellen Smith, Occurrence of newer β-lactamases in Klebsiella pneumoniae isolates from 24 U.S. Hospitals 46:12, p. 3837 - 3842 2002
Journal of clinical microbiology Pérez-Pérez F. Javier, Detection of plasmid-mediated AmpC β-lactamase genes in clinical isolates by using multiplex PCR 40:6, p. 2153 - 2162 2002
Journal of Antimicrobial Chemotherapy Hanson Nancy D., Unusual Salmonella enterica serotype Typhimurium isolate producing CMY-7, SHV-9 and OXA-30 β-lactamases 49:6, p. 1011 - 1014 2002
Journal of Antimicrobial Chemotherapy Reisbig Mark D., The ACT-1 plasmid-encoded AmpC β-lactamase is inducible 49:3, p. 557 - 560 2002
Diagnostic Microbiology and Infectious Disease Hanson Nancy D., Enzymatic characterization of TEM-63, a TEM-type extended spectrum β-lactamase expressed in three different genera of Enterobacteriaceae from South Africa 40:4, p. 199 - 201 2001
ChemInform Hanson N. D., ChemInform Abstract: Regulation of Inducible AmpC β-Lactamase Expression Among Enterobacteriaceae 31:6, p. no - no 2000
Current Pharmaceutical Design Hanson N. D., Regulation of inducible AmpC beta-lactamase expression among enterobacteriaceae 5:11, p. 881 - 894 1999
Journal of Antimicrobial Chemotherapy Hanson Nancy D., Molecular characterization of a multiply resistant Klebsiella pneumoniae encoding ESBLs and a plasmid-mediated AmpC 44:3, p. 377 - 380 1999
Antimicrobial agents and chemotherapy Pitout J. D.D., β-lactamases responsible for resistance to expanded-spectrum cephalosporins in Klebsiella pneumoniae, Escherichia colt, and Proteus mirabills isolates recovered in South Africa 42:6, p. 1350 - 1354 1998
Antimicrobial agents and chemotherapy Pitout Johann D.D., Plasmid-mediated resistance to expanded-spectrum cephalosporins among Enterobacter aerogenes strains 42:3, p. 596 - 600 1998
Virus Research Hanson Nancy, The herpes simplex virus type 2 gene which encodes the large subunit of ribonucleotide reductase has unusual regulatory properties 34:3, p. 265 - 280 1994
Virology Bratanich Ana C., The latency-related gene of bovine herpesvirus 1 inhibits the activity of immediate-early transcription unit 1 191:2, p. 988 - 991 1992
Journal of Virology Hanson N. D., Parvovirus NS1 stimulates P4 expression by interaction with the terminal repeats and through DNA amplification 65:8, p. 4325 - 4333 1991
Experimental Mycology Hanson Nancy Dohse, Membrane protein variation in Dictyostelium mucoroides during sorocarp and macrocyst development 11:4, p. 354 - 359 1987
Presentations
ASM Distinguished Lecturer: The Regulation of β-Lactamase ProductionHow many variations can there be? 2016
American Society for Microbiology Distinguished Lecturer Program: Baltimore MD Molecular Diagnostics: Current and Future Applications for Detection of Antibiotic Resistance Mechanisms 2016
November 7, 2015: Invited Symposium Speaker for the Association for Molecular Pathologists. Title of the talk: Molecular Detection of β-Lactamase Genes: Why and How? 2015
October 7, 2015. Invited Lecturer selected by the graduate students at K-State University. Title of the talk: Molecular Detection of β-Lactamase Genes: The Human/Animal Connection 2015
September 26, 2015. Dr. Hanson gave the American Society Distinguished Lecture for the joint meeting for the Kentucky/Tennessee Branch of the American Society of Microbiology. Title of the talk: The Global Explosion of Gram-negative β-lactamase Producers: What can be done? 2015
September 24, 2015. Dr. Hanson gave a seminar to the Biology Department at Middle Tennessee State University. Title of the talk: The Regulation of β-Lactamase Production: How many variations can there be? 2015
Interscience Conference on Antimicrobial Agents and Chemotherapy. title: 7-plex and 10-plex PCR assays for the detection of ampC, blaCTX-M, and 5 carbapenemase genes using rapid PCR amplification. 2015
7-plex and 10-plex PCR assays for the detection of ampCs, blaCTX-Ms, and 5 carbapenemase genes using rapid PCR amplification. 2015 In Abstracts of the 115th American Society of Microbiology. New Orleans, LA. 2015
KPC translational efficiency differs between sequence type 131 (ST131) and non-ST 131 E. coli. L.B. Harrison, Y. Doi, N.D. Hanson. 2015 In Abstracts of the 115th American Society of Microbiology. New Orleans, LA. Poster Presentation. 2015
Development of an eighteen-minute multiplex PCR assay for the simultaneous detection of 6 OXA carbapenemases. R.C. Fowler and N. D. Hanson. 2015 In Abstracts of the 115th American Society of Microbiology. New Orleans, LA. Poster Presentation. 2015
American Society of Microbiology Distinguished Lecturer: Regulation of Beta-lactamase production: How many variations can there be? Northern California ASM Branch Meeting. 2015
American Society of Microbiology Distinguished Lecturer: Global Explosion of Gram‐Negative β‐lactamase Producers: What can be done? Northern California ASM Branch Meeting. 2015
Gram-Negative Innovation Day: "Learn & Imagine The Global Explosion of Gram‐Negative β‐lactamase Producers: What can be done?" Lexington, MA. Sponsored by Cubist 2014
One 22-minute multiplx assay for the detection of 9 targets including ampCs, ESBLs, MBLs, and KPCs using Rapid PCR Amplification. N.D. Hanson Speaker. In Abstracts of the 54th Interscience Conference on Antimicrobial Agents and Chemotherapy. Washington DC. Sponsored by Streck. 2014
1. The Rapid Detection of ampC Resistance Genes in Gram-negative Bacteria. N.D. Hanson Speaker. In Abstracts of the 114th American Society of Microbiology. Boston MA. Sponsored by Streck. 2014
Identification of Promoter Sequences required for the Expression of the Porin Gene opdQ of Pseudomonas aeruginosa. Randal Fowler and N. D. Hanson. 2014. In Abstracts of the 114th American Society of Microbiology. Boston MA. Poster Presentation. 2014
Overproduction of the Porin OpdQ is Associated but not Responsible for Multidrug Supersusceptibility (SS) in Carbapenem-selected Mutants of Pseudomonas aeruginosa (PA). R. Fowler and N. D. Hanson. 2014. In Abstracts of the 114th American Society of Microbiology. Boston MA. Poster Presentation. 2014
One sixteen minute multiplex assay for the detection of AmpCs, ESBLs, MBLs and KPCs using Rapid PCR Amplification. C. Geyer, S. Morrow, and, N. Hanson. 2014. In Abstracts of the 24th European Congress of Clinical Microbiology and Infectious Diseases. Barcelona, Spa 2014
The Discordant Relationship Between CTX-M-15 mRNA and Protein Production does not Interfere With Beta-Lactam/Beta-Lactamase Inhibitor Combination Susceptibilities in Escherichia coli. C.Geyer, R. Fowler, and N. Hanson. 2014. In Abstracts of the 24th European Congress of Clinical Microbiology and Infectious Diseases. Barcelona, Spain. 2014
The mRNA half-life of CTX-M-15 transcripts is controlled by a factor encoded on the blaCTX-M-15 containing plasmid. C. Geyer, and N. Hanson. 2014. In Abstracts of the 24th European Congress of Clinical Microbiology and Infectious Diseases. Barcelona, Spain. 2014
Gram-negative Summit: Gram-negative Multi-Drug Resistant Mechanisms. June 18, 2013. Boston MA. Sponsored by Cubist. 2013
1. Rapid Detectin of KPC Gene Variants in Gram-negative Pathogens Using High-Resolution Melting and ScreenClust Analyses. N.D. Hanson Speaker. In Abstracts of the 115th American Society of Microbiology. Denver CO. Sponsored by Qiagen. 2013
Identification of family-specific plasmid-mediated AmpC β-lactamase (pmAmpC) genes using multiplex PCR and High Resolution Melth (HRM) Analysis. C. N. Geyer and N. D. Hanson. 2013. In Abstracts of the 113th American Society of Microbiology. Denver CO. Poster Presentation. 2013
1. Carbapenem resistance is not associated with virulence of Pseudomonas aeruginosa using the Dictyostelium discoideum virulence model. R. Fowler, A.T. Weber, and N. D. Hanson. 2012. In Abstracts of the 52th Interscience Conference on Antimicrobial Agents and Chemotherapy. San Francisco, CA Poster Presentation. 2012
High resolution melting analysis allows rapid detection and differentiation of blaKPC alleles in Gram-ngative pathogens. A. L. Roth, M. Kovarik, and N.D. Hanson. 2012. In Abstracts of the 52th Interscience Conference on Antimicrobial Agents and Chemotherapy. San Francisco, CA. Poster Presentation. 2012
Evaluation of blaCTXM14 and blaCTXM15 Identifies Differential Gene Expression Among Sequence Type 131 and Non-ST131 E. coli. C. N. Geyer, S. Weissman, P. Hawkey and N. D. Hanson. 2012. In Abstracts of the 52th Interscience Conference on Antimicrobial Agents and Chemotherapy. San Francisco, CA. Poster Presentation. 2012
Kinetic Characterization of a novel VIM (VIM-28) Metallo--lactamase in Pseudomonas aeruginosa isolates from Egypt. A. Yoshizumi, Y. Ishii, T.S.El-Mahdy, N. D. Hanson, and K. Tateda. 2012. In Abstracts of the 52th Interscience Conference on Antimicrobial Agents and Chemotherapy. San Francisco, CA. Poster Presentation. 2012
HudsonAlpha Institute. Huntsville, Alabama. Institutional Seminar Speaker. August 9, 2012. Title: "The Impact of Molecular Testing to Control the Antibiotic Resistance Crisis Caused by Gram-Negative Pathogens" 2012
Symposium Talk for the Regional American Society of Microbiology Meetngs in Kansas City. "Mobile Genetic Elements Associated with Beta-Lactam Resistance 2006
Amber Schmidtke and Nancy D Hanson. Molecular Characterization of the ampD promoter of Pseudomonas aeruginosa. Oral presentation 2006
Efflux Pump and Porin Alterations in a Supersuceptible (SS) Strain of P. aeruginosa (PA). D. J. Wolter, J. A. Black, P. D. Lister, N. D. Hanson. 2005. In Abstracts of the 45th Interscience Conference on Antimicrobial Agents and Chemotherapy. Washington, D.C. Poster presentation 2005
Phenotypic Reversion of Imipenem Hypersusceptibility among mexCD-oprJ-Oeverexpressing P. aeruginosa: a complex system becomes more complex. 2005. D. J. Wolter, N. D. Hanson, P.D. Lister. In Abstracts of the 45th Interscience Conference on Antimicrobial Agents and Chemotherapy. Washington, D.C. Oral Presentation 2005
In Vitro Development of Resistance to DX-619 (DX) and Other Quinolones (Qs) in Enterococcus faecium. P. Wickman, J. A. Black, E. Smith Moland, K. S. Thomson, and N. D. Hanson. 2005. In Abstracts of the 45th Interscience Conference on Antimicrobial Agents and Chemotherapy. Washington, D.C. Poster Presentation 2005
A Novel Mechanism of AmpD-Mediated Derepression in an Isolate of Citrobacter freundii. A. J. Schmidtke and N.D. Hanson. 2005 In Abstracts of the 45th Interscience Conference on Antimicrobial Agents and Chemotherapy. Washington, D.C. Oral presentation 2005
Correlation of ampC Induction with PBP Binding in Enterobacter cloacae. B. Abdalhamid, P. A. Wickman, and N. D. Hanson. 2005 In Abstracts of the 45th Interscience Conference on Antimicrobial Agents and Chemotherapy. Washington, D.C. oral presentation 2005
Apparent Acquisition of ESBL Leading to Treatment Failure during Cefepime (FEP) Therapy of Klebsiella pneumoniae (KP) Bacteremia. W. Song, E. Smith Moland, N. D. Hanson, J. S. Lewis, J. H. Jorgensen, and K. S. Thomson. 2005. In Abstracts of the 45th Interscience Conference on Antimicrobial Agents and Chemotherapy. Washington, D.C Poster Presentation 2005
Invited Symposium Speaker: American Society of Microbiology 45th Interscience Conference on Antimicrobial Agents and Chemotherapy: Washington DC, USA: December 2005. "Detection of Extended Spectrum -lactamases and Plasmid-mediated AmpC -lactamases Using Phenotypic and Molecular Tests. 2005
OXA-30-Like -lactamases in E. coli Hydrolyze Cefepime. E. S. Moland, N. D. Hanson, C. Shubert, K. S. Thomson. 2005. In Abstracts of the 45th Interscience Conference on Antimicrobial Agents and Chemotherapy. Washington, D.C. Poster presentation 2005
Society for General Microbiology, Edinburgh, Scotland. Symposium Lecture April 2004. Title: Molecular Mechanisms of AmpC Gene Expression and the Clinical Implications Associated with Gram-negative Pathogens. 2005
A community-wide outbreak of clonally related Escherichia coli producing CTX-M-type -lactamases in the Calgary Health Region (CHR).2004. J. D. D. Pitout, D. B. Gregson, D. L. Church, K. B. Laupland, S. Elsayed, and N. D. Hanson. In Abstracts of the 44th Interscience Conference on Antimicrobial Agents and Chemotherapy. Washington, D.C. 2004
Klebsiella isolates that Co-produce ESBL and inducible DHA-like plasmid-mediated AmpC beta-lactamases from Baltimore, MD and Tampa, FL. Black, J.A., E.S. Moland, A. Hossain, J.A. Johnson, M. Campbell, T.J. Lockhart, L.B. Olson, K. S. Thomson, and N. D. Hanson. In Abstracts of the 44th Interscience Conference on Antimicrobial Agents and Chemotherapy. Washington, D.C. 2004
Occurrence of Proteus mirabilis producing FOX-5 plasmid-mediated AmpC beta-lactamase in USA. Black, J.A., E.S. Moland, A. Hossain, G.A. Denys, , T.J. Lockhart, L.B. Olson, K. S. Thomson, and N. D. Hanson. In Abstracts of the 44th Interscience Conference on Antimicrobial Agents and Chemotherapy. Washington, D.C. 2004
Increased Expression of ampC in Pseudomonas aeruginosa mutants following exposure to ciprofloxacin (CIP). D. J. Wolter, N.D. Hanson, and P.D.Lister. In Abstracts of the 44th Interscience Conference on Antimicrobial Agents and Chemotherapy. Washington, D.C. 2004
Beta-lactam MICs and differential expression of blaCMY-2 reflect dual promoter activity. M.D. Reisbig and N.D. Hanson. 2004. In Abstracts of the 44th Interscience Conference on Antimicrobial Agents and Chemotherapy. Washington, D.C. 2004
Comparison of ampC transcript half-life among three genera of Enterobacteriaceae. B. Abdalhalmid and N. D. Hanson. 2004. In Abstracts of the 44th Interscience Conference on Antimicrobial Agents and Chemotherapy. Washington, D.C. 2004
Development of a Model System to Determine the Effect of ampD mutations on -lactam Resistance. 2004. A. J. Schmidtke and N.D. Hanson. In Abstracts of the 44th Interscience Conference on Antimicrobial Agents and Chemotherapy. Washington, D.C. 2004
The First Occurrence of a Pseudomonas aeruginosa in the United States (US) Producing and IMP Metallo--lactamase (MBL). N.D.Hanson, A. Hossain, L. Buck, E.S. Moland, and K.S. Thomson. 2004 In Abstracts of the 44th Interscience Conference on Antimicrobial Agents and Chemotherapy. Washington, D.C. 2004
Australian Society of Microbiology Antimicrobial Meeting, Queensland Regional Meeting. Morton Bay Research Facility, North Stradbroke Island, Brisbane Australia. July 2004. World Wide Emergence of Beta-lactam Resistance: The Need for Molecular Diagnostics. 2004
University of Queensland, Brisbane, Australia: Department of Veterinary Science. July 2004. The Molecular Mechanisms Involved in AmpC-Mediated Resistance: A Complex Process. 2004
Australian Society of Microbiology Antimicrobial Meeting, Grand Rounds: Womens and Childrens Hospital, Adelaide, Australia: July 2004. ESBLs and AmpCs: Whats the Difference? 2004
Australian Society of Microbiology Antimicrobial Meeting, Grand Rounds: Concord Hospital, Sydney Australia: July 2004. ESBLs and Plasmid-mediated AmpC in Gram-Negative Bacteria- What are the differences? 2004
Survey of cefoxitin (FOX) non-wusceptible (NS) E. coli urine isolates (UIs) reveals a high incidence of plasmid-encoded AmpC (pAmpC) -Lactamase (L) Producers. 2004. M.D. Reisbig, S.J. Cavalieri, H.A. Hashish, R.V. Goering, and N.D. Hanson. In Abstracts of the 104th General Meeting of the American Society for Microbiology. New Orleans, LA. 2004
18. Laboratory Diagnosis of Escherichia coli and Klebsiella spp. producing CTX-M--lactamases. 2004. J. D. D. Pitout, A. Hossain, D. L. Church, N. D. Hanson. In Abstracts of the 104th General Meeting of the American Society for Microbiology. New Orleans, LA. 2004
Paediatric infection due to multi-resistant Salmonella Infantis carrying blaCMY-2, blaTEM-1, blaCTX-M-15 and blaSHV-5 -lactamases. 2004. E. Liebana, J. Martinez-Urtaza, M. Batchelor, C. Torres, L. Brinas, L.A. Lagos, B. Abdalhamid, N.D. Nanson, F.A. Clifton-Hadley, R.H. Davies. In Abstracts of the 104th General Meeting of the American Society for Microbiology. New Orleans, LA. 2004
16. Evaluation of cefepime (FEP) with and without clavulanic acid (CA) for the detection of ESBLs (Extended Spectrum Beta-Lactamases) in Enterobacteriaceae species. 2004. E. Smith Moland, T.J. Lockkhart, J.A. Black, L.B. Olson, A. HOssain, N.D. Hanson, and K.S. Thomson. In Clinical Microbiology and Infection. 14th European Congress of Clinical Microbiology and Infectious Diseases. 2004
Abdalhamid, B. and N. D. Hanson. Differential half-life of the ampC transcript between three genera of Enterobacteriaceae. April 2004. In Abstracts of the Regional American Society for Microbiology, Missouri Valley Branch. Kansas City, Missouri. 2004
Schmidtke, A. and N. D. Hanson. AmpD mutations in E. coli. April 2004. In Abstracts of the Regional American Society for Microbiology, Missouri Valley Branch. Kansas City, Missouri. 2004
Puerto Rico Veterans Administration Hospital: Infectious Disease Fellows: February 2004. World Wide Emergence of -lactam and Fluoroquinolone Resistance: The Need for Molecular Diagnostics. 2004
University of Puerto Rico, Department of Microbiology and Medical Zoology Graduate Seminar: February 2004. The Complexities of Molecular Mechanisms Involved in AmpC-Mediated Resistance. 2004
University of Puerto Rico School of Medicine: Grand Rounds. February 2004. World Wide Emergence of -lactam and Fluoroquinolone Resistance: The Need for Molecular Diagnostics. 2004
Childrens Hospital, Grand Rounds. January 2004. Evolution of Antibiotic Resistance and the Concomitant Decrease in Therapeutic Options for Lung Infections in the Cystic Fibrosis Patient. 2004
Emergence of Fluoroquinolone (FQ) Resistant Pseudomonas aeruginosa (PA) in a Cystic Fibrosis (CF) Patient: Discordance between MexEF-OprN and Carbapenem Susceptibility. 2003. D.J. Wolters, J. Black, D. Acquazzino, R. Goering, P.Sammut, N. Hanson. In Abstracts of the 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, Illinois. Oral Presentation 2003
Molecular Analysis of 10 Putative Efflux Genes in Streptococcus pneumoniae (SP) Reveals Widespread Differences Between Wildtype (WT) Strains and Multi-Drug Resistant (MDR) Clinical Isolates. 2003. P.A. Wichman, K.S. Thomson, N.D. Hanson. In Abstracts of the 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, Illinois. Oral Presentation 2003
A Novel Mechanism of Resistance to Ciprofloxacin (CIP) and Ethidium Bromide (EB) in Streptococcus pneumoniae (SP): Downregulation of a Putative Permease. 2003. P.A. Wichman, G. A. Perry, K.S. Thomson, N. D. Hanson. In Abstracts of the 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, Illinois. Oral Presentation 2003
Insertional Inactivation of oprD in Clinical Isolates of Pseudomonas aeruginosa Leading to Carbapenem Resistance. 2003. D.J. Wolter, N. Hanson, P. Lister. In Abstracts of the 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, Illinois. Oral Presentation 2003
Prevalence of Plasmid-mediated AmpC beta-lactamases in Klebsiella pneumoniae (KP), Klebsiella oxytoca (KO), Proteus mirabilis (PM), and Salmonella (S) Isolates from 42 ICU and 21 non-ICU Sites in the United States. 2003 J.A. Black, E.Smith Moland, A. Hossain, T.J. Lockhard, L.B. Olson, K.S. Thomson, N.D. Hanson. In Abstracts of the 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, Illinois. 2003
Deletional Analysis of the blaMir-1 Upstream Region Reveals a Novel Promoter Necessary for High-Level Expression and beta-Lactam Resistance. 2003. M. D. Reisbig and N. D. Hanson. In Abstracts of the 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, Illinois 2003
Citrobacter freundii from Canada Producing A Novel CTX-M Gene, blaCTX-M-30. 2003. A. Abdalhamid, J.D.D. Pitout, N.D. Hanson. In Abstracts of the 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, Illinois. 2003
Surveillance for Escherichia coli Producing CTX-M-Type -Lactamases in the Calgary Health Region (CHR). 2003. J.D.D. Pitout, K.B. Laupland, D.L. Church, S. Elsayed, D. Gregson, N.D. Hanson. In Abstracts of the 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, Illinois. 2003
Detection of CTX-M-Like ESBLs in Thirteen States within the USA. 2003. E.S. Moland, J.A. Black, K.S. Thomson, N.D. Hanson, T. J. Lockhart, L.B. Olson, A. Hossain. 2003
Characterisation of Beta-lactamases Responsible for Resistance to Extended-Spectrum Cephalosporins in E. coli and S. enterica from U.K. Food Animals. 2003. E. Liebana, M. Gibbs, C. Clouting, L. Barker, F. Clifton-Hadley, E. Pleydell, B. Abdalhamid, N. Hanson, L. Martin, C. Poppe, R. Davies. In Abstracts of the 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, Illinois. 2003
E. coli producing KPC-3 carbapenem hydrolyzing enzyme (CHE). 2003. T. Hong, E.S. Moland, B. Abdalhamid, N.D. Hanson, J. Wang, C. Sloan, D. Fabian, A. Farajallah, J. Levine, K.S. Thomson. 2003. In Abstracts of the 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, Illinois. 2003
Prevalence of ESBLs in the United States. 2003. E. Smith Moland, J.A. Black, N.D. Hanson, A. Hossain, B. Abdalhamid, W. Song, T.J. Lockhart, L.B. Olson, K.S. Thomson. In Abstracts of the 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, Illinois. 2003
Occurrence of a CTX-M-1-like ESBL in a U.S. Isolate of Citrobacter freundii (CF). 2003. S.E. Sharp, C. Suarez, E. Smith Moland, A. Hossain, N.D. Hanson, and K.S. Thomson. In Abstracts of the 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, Illinois. 2003
A New Quality Control Strain for Routine Testing for Production of Extended Spectrum Beta-Lactamases (ESBL). 2003. J.E. Mortensen, M. Bernier, L. Gray, S. Doland, E.S. Moland, B. Abdalhamid, N.D. Hanson. In Abstracts of the 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, Illinois. 2003
First Report of Plasmid-encoded (PE) Carbapenem Hydrolyzing Enzyme (CHE) KPC-2 in Enterobacter cloacae (EC). 2003 A. Hossain, M.J. Ferraro, R.M. Pino, R.B. Dew III, E.S. Moland, T.J. Lochart, K.S. Thomson, R.V. Goering, and N.D. Hanson. In Abstracts of the 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, Illinois. 2003
A. Hossain, Reisbig. M.D., and N.D. Hanson. High-level expression of the plasmid-encoded AmpC gene, blaCMY-7 does not compromise the virulent phenotype of a strain of Salmonella typhimurium. In Abtracts of the 13th European Congress of Clinical Microbiology and Infectious Disease, Glasgow, United Kingdom 2003
M.D. Reisbig and N.D. Hanson. Variations in -Lactam Susceptibilities Between Organisms Expressing the Plasmid-Encoded AmpC beta-lactamase CMY-2 is Attributed to Variable Gene Expression. In Abstracts of the 13th European Congress of Clinical Microbiology and Infectious Diseases, Glasgow, United Kingdom 2003
Daniel J. Wolter, Nancy D. Hanson, and Philip D. Lister. Multi-Drug Resistance Associated with mexXY Expression in Clinical Isolates of Pseudomonas aeruginosa from a Texas Hospital. In Abstracts of the 13th Congress of Clinicacl Microbiology and Infectious Diseases, Glasgow, United Kingdom 2003
A. Hossain. P. Wickman, K. S. Thomson and N.D. Hanson Molecular analysis of Streptococcus pneumoniae mutants selected by DK-507k, an investigational fluoroquinolone. In Abstracts of the 13th European Congress of Clinical Microbiology and Infectious Diseases, Glasgow, United Kingdom 2003
D WOLTER, M. REISBIG, N. HANSON, P. LISTER. Pharmacodynamics of Cefepime-Aztreonam Combination against Pseudomonas aeruginosa Isolated from Cystic Fibrosis Patients. In Abstracts of the 13th European Congress of Clinical Microbiology and Infectious Diseases, Glasgow, United Kingdom 2003
P.A. Wickman*, A. Hossain, K.S. Thomson, and N.D. Hanson Differences in selection of efflux-mediated fluoroquinolone resistance in penicillin-susceptible and -resistant Streptococcus pneumoniae after repeated exposure to ciprofloxacin and moxifloxacin. In Abstracts of the 13th European Congress of Clinical Microbiology and Infectious Diseases, Glasgow, United Kingdom. 2003
Oklahoma State University: Stillwater Oklahoma. October 28, 2002. The Complexities of Molecular Mechanisms Involved in AmpC Beta-lactamase-mediated Resistance 2002
Discovery of CTX-M-like ESBLs in E. coli Isolates from Five States in the USA. 2002. E. Smith Moland, S. Pottumarthy-Boddu, J.A. Black, A. Hossain, N.D. Hanson, K.S. Thomson. In Abstracts Addendum of the 42nd Interscience Conference on Antimicrobial Agents and Chemotherapy. San Diego, CA. 2002
Pitout, J.D., E.Smith-Moland, S. Elsayed, N. Hamilton, J. Conly, D. Church, N. Hanson. 2002. A Novel Carbapenem-Hydrolyzing Enzyme (CHE) Produced by an Enterobacter cloacae Isolate from Canada. In Abstracts of the 42nd Interscience Conference on Antimicrobial Agents and Chemotherapy. San Diego, CA. 2002
Wolter, D. J., N.D. Hanson, and P. D. Lister. 2002. Continued Expression of mexCD-oprJ Among Phenotypic Revertants of Pseudomonas aeruginosa (PA) that Have Lost Their Fluoroquinolone Resistance. In Abstracts of the 42nd Interscience Conference on Antimicrobial Agents and Chemotherapy. San Diego, CA. 2002
Wolter, D. J., T. J. Lockhart, N.D. Hanson, and P.D. Lister. 2002. Imipenem Hypersusceptibility Among mexCD-oprJ Hyperexpressing Mutants of Pseudomonas aeruginosa does not Involve Decreased expression of ampC or Increased Expression of oprD. In Abstracts of the 42nd Interscience 2002
Hossain, A., E.S. Moland, J.A. Black, N.D. Hanson, K.S. Thomson. 2002. DQ-113: In Vitro development and Mutational Analysis of Resistance in Staphylococcus aureus, Penicillin Resistant Streptococcus pneumoniae (PRSP) and Vancomycin Resistant Enterococci (VRE). In Abstracts of the 42nd Interscience Conference on Antimicrobial Agents and Chemotherapy. San Diego, CA. 2002
Reisbig, M.D. and N.D. Hanson. 2002. Therapeutic Implications for the Plasmid-Encoded (PE) AmpC beta-Lactamase, ACT-1, Expressed in ampD- E. coli. In Abstracts of the 42nd Interscience Conference on Antimicrobial Agents and Chemotherapy. San Diego, CA. 2002
University of Kansas, St. Lukes Hospital. October 15, 2002. ESBLs and AmpC Beta-lactamases: What's the Difference 2002
ESBLs and AmpC beta-lactamases: Whats the Difference? 1. Irish Society of Clinical Microbiology: Dublin Ireland Invited Speaker 2002
Great Plains State Society for Molecular Biology and Genetics: Omaha, Nebraska: June 2002. Invited speaker "AmpC-mediated resistance in Gram-negative bacteria: Questions but not many answers." 2002
American Society of Microbiology Symposium Speaker: Salt Lake City, Utah, USA: May 2002. "AmpC beta-Lactamases: A Conundrum." 2002
Wolter, D.J., N.D. Hanson, G. Haynatzki, and P.D. Lister. 2002. Efflux-Mediated Resistance Among Pseudomonas aeruginosa: Complex Regulation of a Complex Resistance Mechanism. In Abstracts of the 102nd General Meeting of the American Society for Microbiology. Salt Lake City, Utah. 2002
Reisbig, M.D. and N.D. Hanson. 2002. The Role of Gene Copy Number in Overall Expression of ampC Genes of Enterobacter cloacae Origin. The 102nd General Meeting of the American Society for Microbiology. Salt Lake City, Utah. 2002
Morrow, S.S. and N.D. Hanson. 2002. Differentiation of Multiple SHV or FOX Genes Using Denaturing High Performance Liquid Chromatography. 2002. In Abstracts of the 102nd General Meeting of the American Society for Microbiology. Salt Lake City, Utah. 2002
Wickman, P.A., A. Hossain, K.S. Thomson, and N.D. Hanson. 2002. Moxifloxacin has Reduced Potential to Select Mutational Fluoroquinolone Resistance in Streptococcus pneumoniae. In Abstracts of the 102nd General Meeting of the American Society for Microbiology. Salt Lake City, Utah. 2002
Moland, E.S., K.K. Sandu, M.R. Pincus, J.A. Black, M.D. Reisbig, N.D. Hanson, K.S. Thomson. 2002. A Simple Phenotypic Approach to the Detection of Inducible Plasmid-mediated AmpC -lactamse (pAmpC) Production in Two New York Isolated of Klebsiella pneumoniae (KP). In Abstracts of the 102nd General Meeting of the American Society for Microbiology. Salt Lake City, Utah. 2002
Moland, E.S., J. Johnson, J.A. Black, T.J. Lockhart, A. Hossain, V.L. Herrera, R.V. Goering, N.D. Hanson, and K.S. Thomson. 2001. Klebsiella pneumoniae (KP) Isolates Producing a Carbapenem Hydrolyzing Enzyme (CHE). In Abstracts of the 41st Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, Illinois. 2001
Coudron, P.E., S.M. Tallent, E.S. Moland, N.D. Hanson, M.B. Edmond, R.P. Wenzel. 2001. Occurrence of Extended-Spectrum (ESBL) and AmpC Beta-Lactamases (BLs) in U.S. Bacteremic Isolates of Klebsiella pneumoniae (Kp): Two Isolates Harbor Inducible Plasmid-Mediated ACT-1-Like BLs. In Abstracts of the 41st Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, Illinois. 2001
Moland, E.S., T.J. Cleary, M.D. Reisbig, Y. Jiang, P.E. Coudron, T.J. Lockhart, N.D. Hanson, K.S. Thomson. 2001. Occurrence of Inducible Plasmid-mediated AmpC -lactamase (ipAmpC), DHA-1, in a Miami Isolate of Klebsiella pneumoniae: New Implications for Susceptibility Testing? In Abstracts of the 41st Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, Illinois. 2001
Hossain, A., E.S. Moland, J.A. Black, S.A. Chartrand, N.D. Hanson, K.S. Thomson. 2001. A New Fluoroquinolone (FQ) With a Low Frequency of Mutational Resistance in MRSA. In Abstracts of the 41st Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, Illinois. 2001
Herrera, V.L. and N.D. Hanson. 2001. Complex Expression of Novel Plasmid-mediated AmpC -Lactamase Gene. In Abstracts of the 41st Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, Illinois.Chicago, Illinois. 2001
Jiang, Y., E.S. Moland, Y.Ni, N.D. Hanson. 2001. Novel Mutations in the Promoter and Attenuator Regions of Hyperproducing AmpC E. coli strains from China. In Abstracts of the 41st Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, Illinois. 2001
Hanson, N.D., S.A. Neville, I.B. Gosbell, A. Hossain, E.S. Moland, and K.S. Thomson. 2001. Salmonella enterica serotype Typhimurium producing CMY-7, SHV-9 and OXA-30 -Lactamases. In Abstracts of the 41st Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, Illinois. 2001
Reisbig, M.D. and N.D. Hanson. 2001. The Plasmid-mediated AmpC -Lactamase, ACT-1, is Inducible in a Multiply Resistant Klebsiella pneumoniae Isolate. In Abstracts of the 41st Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, Illinois. 2001
Mahlen, S.D. and N.D. Hanson. 2001. The Stem-Loop Structure in the 5Untranslated Region (5UTR) of the ampC Transcript of Serratia marcescens is Involved in Transcript Stability. In Abstracts of the 41st Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, Illinois. Oral Presentation given by N.D. Hanson. 2001
American Society for Microbiology Regional Meeting. Analysis of the 5' flanking region of a novel plasmid-mediated amp'c beta-lactamase 2001
American Society of Microbiology Regional Meeting. Deletion of secondary structure in the 5' untranslated region of the ampC gene of Serratia marcescens results in a decrease in translational efficiency 2001
American Society for Microbiology Regional Meeting. Inverse relationship in the expression of multi-drug efflux pumps 2001
American Society for Microbiology Regional Meeting. Molecular and phenotypic analysis to determine the influence of moxifoxacin and ciprofloxacin in selecting mutational fluoroquinolone resistance in Streptococcus pneumoniae 2001
American Society for Microbiology Regional Meeting. PCR amplification of the genetically diverse ampC genes of Enterobacter cloacae using the proof-reading enzyme, Pwo 2001
American Society for Microbiology Regional Meeting. The plasmid-mediated AmpC beta-lactamase, ACT-1, is inducible 2001
Regional Medical Student Research Forum. Evaluation of Nucleotide Diversity within Pseudomonas aeruginosa ampC beta-lactamase 2001
University of Nebraska at Lincoln.Graduate Seminar Speaker."The regulation of AmpC Beta-lactamase expression in Enterobacteriaceae." 2001
Regional AAAS meeting. Analysis of the 5' flanking region of the plasmid-mediated ampC gene, ACT-1 reveals an Enterobacter clacae ampR binding sight and an ampR gene. 2000
University of Dublin, Trinity College, Ireland: Annual molecular medicine symposium, Keynote speaker microbial genetics. Title: "The regulation of AmpC Beta-lactamase expression in Enterobacteriaceae." 2000
Medical School of Edinburgh, Scotland "The regulation of AmpC B-Lactamase expression in Enterobacteriaceae and its relationship to resistance." 2000
St. James Hospital, Dublin, Ireland"The regulation of AmpC B-Lactamase expression in Enterobacteriaceae and its relationship to resistance." 2000
University of Nebraska at Omaha.Graduate Seminar Speaker."The regulation of AmpC Beta-lactamase expression in Enterobacteriaceae." 2000
40th Interscience Conference on Antimicrobial Agents and Chemotherapy. toronto Canada. A Novel Growth-Phase Dependent Factor that Binds to the Serratia marcescens ampC gene and correlates with a Decrease in ampC Transcription 2000
Identification, Cloning and Sequencing of a Novel FOX Plasmid-Mediaated AmpC, N.D. Hanson, P. Coudron, E.S. Moland and C.C. Sanders 39th ICAAC. San Francisco 1999
Sequence Analysis of the ampC and ampR Regions of Serratia marcescens Reveals a Unique 5' Untranslated Region in ampC. S.S. Morrow, C.C. Sanders, and N.D. Hanson 39th ICAAC San Francisco, 1999
Molecular Characterization of Mutants Responsible for Dichotomous Fluoroquinolone Resistance in Staphlococcus aureus, 39th ICAAC, San Francisco 1999
Detection and Characterization of the Beta-Lactamases Produced by Citrobacter koseri, ES Moland, KS Thomson, C.C. Sanders, N.D. Hanson, 39th ICACCA San Francisco 1999
Differential Induction of the Chromosomal Beta-Lactamase Gene of Seratia marcescens by beta-Lactam Antibiotics, Missouri Valley Regional ASM, Tulsa, OK; 1999
Cloning and sequencing of the chromosomally encoded ampC and ampR genes of Serratia marcescens, Missouri Valley Regional ASM, Tulsa, OK, 1999
Transcriptional analysis of Serratia marcescens ampC, Mahlen, S.D. C.C. Sanders, and N.D. Hanson,Southwestern and Rocky Mountain Division American Association for the Advancement of Science, Creighton University, Omaha, NE 1999
Outstanding service as a Branch Councilor American Society for Microbiology Outstanding service as a Branch Councilor of the Missouri Valley Branch American Society for Microbiology
Received a one month travel award for the promotion of research to the University of Queensland, Brisbane Australia. Received a one month travel award for the promotion of research to the University of Queensland, Brisbane Australia.