Thomas F . Murray, PhD

Department

Pharmacology and Neuroscience

Position

Adjunct Professor

Books

• Veterinary Psychopharmacology
  Murray Thomas F., Neuropeptides [Book Chapter] 2019
• Veterinary Psychopharmacology
  Murray Thomas F., Biogenic amine neurotransmitters [Book Chapter] 2019
• Veterinary Psychopharmacology
  Murray Thomas F., Amino acid neurotransmitters [Book Chapter] 2019
• Veterinary Psychopharmacology
  Murray Thomas F., General principles of psychopharmacology [Book Chapter] 2019
• Veterinary Psychopharmacology
  Murray Thomas F., Biogenic amine transmitters [Book Chapter] 2019
• Crowell-Davis Sharon L., de Souza Dantas Leticia Mattos, Murray Thomas F., Veterinary psychopharmacology 2019
• Crowell-Davis Sharon, Murray Thomas, Veterinary Psychopharmacology 2008
• Murray Thomas F., Neurosciences in the third millennium 2004
• Methods in Neurosciences
  Orchinik Miles, Murray Thomas F., Steroid Hormone Binding to Membrane Receptors [Book Chapter] 1994

Articles

• Musser B., Murray T. F., Linden J., Vestal R. E., Morgan M. E., Leid M., Erratum 1996

Publications

• Marine Drugs
  Mehrotra Suneet, Pierce Marsha L., Dravid Shashank M., Murray Thomas F., Stimulation of Neurite Outgrowth in Cerebrocortical Neurons by Sodium Channel Activator Brevetoxin-2 Requires Both N-Methyl-D-aspartate Receptor 2B (GluN2B) and p21 Protein (Cdc42/Rac)-Activated Kinase 1 (PAK1)
  20:9 2022
• Medicinal Chemistry Research
  Fang Wei Jie, Murray Thomas F., Aldrich Jane V., Analogs of the κ opioid receptor antagonist arodyn cyclized by ring-closing metathesis retain κ opioid receptor affinity, selectivity and κ opioid receptor antagonism
  30:7, p. 1397 - 1407 2021
• ACS Chemical Neuroscience
  Ferracane Michael J., Stacy Heather M., Murray Thomas F., McLaughlin Jay P., Brice-Tutt Ariana C., Eans Shainnel O., Coleman Jeremy S., Simpson Grant G., Wilson Lisa L., Aldrich Jane V., Design, Synthesis, and Characterization of the Macrocyclic Tetrapeptide cyclo[Pro-Sar-Phe- d -Phe]
  11:9, p. 1324 - 1336 2020
• Journal of Natural Products
  Naman C. Benjamin, Almaliti Jehad, Armstrong Lorene, Caro-Diaz Eduardo J., Pierce Marsha L., Glukhov Evgenia, Fenner Amanda, Spadafora Carmenza, Debonsi Hosana M., Dorrestein Pieter C., Murray Thomas F., Gerwick William H., Discovery and Synthesis of Caracolamide A, an Ion Channel Modulating Dichlorovinylidene Containing Phenethylamide from a Panamanian Marine Cyanobacterium Cf. Symploca Species
  80:8, p. 2328 - 2334 2017
• Journal of Natural Products
  Kinnel Robin B., Mevers Emily, Pereira Alban R., Monroe Emily A., Sherman David, Esquenazi Eduardo, Leao Tiago, Moss Nathan, Korobeynikov Anton, Murray Thomas F., Gerwick William H., Dorrestein Pieter C., A Maldiisotopic Approach to Discover Natural Products: Cryptomaldamide, a Hybrid Tripeptide from the Marine Cyanobacterium Moorea Producens
  80:5, p. 1514 - 1521 2017
• Organic and Biomolecular Chemistry
  Philkhana S. C., Mehrotra Suneet, Murray Thomas F., Reddy D. S., Synthesis and Biological Evaluation of Palmyrolide A Macrocycles as Sodium Channel Blockers Towards Neuroprotection
  14:36, p. 8457 - 8473 2016
• Journal of Medicinal Chemistry
  Joshi A. A., Murray Thomas F., Aldrich J. V., Structure-Activity Relationships of the Peptide Kappa Opioid Receptor Antagonist Zyklophin
  58:22, p. 8783 - 8795 2015
• PLoS One
  Boudreau P. D., Monroe E. A., Mehrotra Suneet, Desfor S., Gerwick W. H., Dorrestein P. C., Murray Thomas F., Korobeynikov A., Sherman D. H., Expanding the Described Metabolome of the Marine Cyanobacterium Moorea producens JHB through Orthogonal Natural Products Workflows
  10:7, p. (23 pages) 2015
• Marine Drugs
  Cao Z., Gerwick W. H., Murray Thomas F., Li X., Zou X., Greenwood Michael, Involvement of JNK and Caspase Activation in Hoiamide A-Induced Neurotoxicity in Neocortical Neurons
  13:2, p. 903 - 919 2015
• Journal of Pharmacology and Experimental Therapeutics
  Cao Zhengyu, Cui Yanjun, Busse Eric, Mehrotra Suneet, Rainier Jon D., Murray Thomas F., Gambierol inhibition of voltage-gated potassium channels augments spontaneous Ca2+ oscillations in cerebrocortical neurons
  350:3, p. 615 - 623 2014
• British Journal of Pharmacology
  Aldrich J. V., Senadheera S. N., Ross N. C., Reilley K. A., Ganno M. L., Eans S. E., Murray Thomas F., McLaughlin J. P., Alanine analogues of [D-Trp]CJ-15,208: novel opioid activity profiles and prevention of drug- and stress-induced reinstatement of cocaine-seeking behaviour
  171:13, p. 3212 - 3222 2014
• Journal of Natural Products
  Mehrotra Suneet, Tello-Aburto Rodolfo, Newar Tara D., Gerwick William H., Murray Thomas F., Maio William A., Duggan Brendan M., Detailed analysis of (-)-palmyrolide a and some synthetic derivatives as voltage-gated sodium channel antagonists
  77:11, p. 2553 - 2560 2014
• ACS Medicinal Chemistry Letters
  Lesma G., Salvadori S., Airaghi F., Murray Thomas F., Recca T., Sacchetti A., Balboni G., Silvani A., Structural and Biological Exploration of Phe(3)-Phe(4)-Modified Endomorphin-2 Peptidomimetics
  4:8, p. 795 - 799 2013
• Proceedings of the National Academy of Sciences of the United States of America
  George Joju, Gerwick W. H., Murray Thomas F., Baden D. G., Bidirectional influence of sodium channel activation on NMDA receptor-dependent cerebrocortical neuron structural plasticity, p. 19840 - 19845 2012
• Journal of Natural Products
  Malloy Karla L., Suyama Takashi L., Engene Niclas, Debonsi Hosana, Cao Zhengyu, Matainaho Teatulohi, Spadafora Carmenza, Murray Thomas F., Gerwick William H., Credneramides A and B
  75:1, p. 60 - 66 2012
• Journal of Natural Products
  Malloy Karla L., Suyama Takashi L., Engene Niclas, Debonsi Hosana, Cao Zhengyu, Matainaho Teatulohi, Spadafora Carmenza, Gerwick William H., Murray Thomas F., Credneramides A and B: Neuromodulatory Phenethylamine and Isopentylamine Derivatives of a Vinyl Chloride-Containing Fatty Acid from cf. Trichodesmium sp nov
  75:1, p. 60 - 66 2012
• Journal of Natural Products
  Engene Niclas, Esquenazi Eduardo, Byrum Tara, Villa Francisco A., Cao Zhengyu, Murray Thomas F., Dorrestein Pieter C., Gerwick Lena, Gerwick William H., Choi Hyukjae, Phylogeny-guided isolation of ethyl tumonoate a from the marine cyanobacterium cf. Oscillatoria margaritifera
  74:8, p. 1737 - 1743 2011
• Molecular Pharmacology
  Kelamangalath L., Dravid Shashank M., George J., Aldrich J., Murray Thomas F., Kappa-opioid receptor inhibition of calcium oscillations in spinal cord neurons
  79:6, p. 1061 - 1071 2011
• Environmental Health Perspectives
  Cao Zhengyu, Shafer Timothy J., Crofton Kevin M., Gennings Chris, Murray Thomas F., Additivity of Pyrethroid Actions on Sodium Influx in Cerebrocortical Neurons in Primary Culture
  119:9, p. 1239 - 1246 2011
• Journal of Pharmacology and Experimental Therapeutics
  Cao Zhengyu, Murray Thomas F., Shafer T. J., Mechanisms of pyrethroid insecticide-induced stimulation of calcium influx in neocortical neurons
  336:1, p. 197 - 205 2011
• Toxicological Sciences
  Cao Zhengyu, Lepage K. T., Frederick M. O., Nicolaou K. C., Murray Thomas F., Involvement of Caspase Activation in Azaspiracid-Induced Neurotoxicity in Neocortical Neurons
  114:2, p. 323 - 334 2010
• Journal of Pharmacology and Experimental Therapeutics
  Jabba S. V., Prakash A., Dravid Shashank M., Gerwick W. H., Murray Thomas F., Antillatoxin, a Novel Lipopeptide, Enhances Neurite Outgrowth in Immature Cerebrocortical Neurons Through Activation of Voltage-Gated Sodium Channels
  332:3, p. 698 - 709 2010
• BMC Neuroscience
  Cao Zhengyu, Gerwick William H., Murray Thomas F., Antillatoxin is a sodium channel activator that displays unique efficacy in heterologously expressed rNa(v)1.2, rNa(v)1.4 and rNa(v)1.5 alpha subunits
  11, p. 154 - 154 2010
• Journal of Medicinal Chemistry
  Patkar Kshitij A., Murray Thomas F., Aldrich Jane V., The effects of C-terminal modifications on the opioid activity of [N-benzylTyr1]dynorphin A-(1-11) analogues
  52:21, p. 6814 - 6821 2009
• Journal of Medicinal Chemistry
  Fang Wei Jie, Cui Yanjun, Murray Thomas F., Aldrich Jane V., Design, synthesis, and pharmacological activities of dynorphin A analogues cyclized by ring-closing metathesis
  52:18, p. 5619 - 5625 2009
• Journal of Neuroscience
  George Joju, Dravid Shashank M., Prakash Anand, Xie Jun, Peterson Jennifer, Jabba Sairam V., Baden Daniel G., Murray Thomas F., Sodium channel activation augments NMDA receptor function and promotes neurite outgrowth in immature cerebrocortical neurons
  29:10, p. 3288 - 3301 2009
• Journal of Medicinal Chemistry
  Patkar Kshitij A., Murray Thomas F., Aldrich Jane V., The Effects of C-terminal Modifications on the Opioid Activity of [N-BenzylTyr1]Dynorphin A-(1-11) Analogs
  52:21, p. 6814 - 6821 2009
• Advances in experimental medicine and biology
  Fang Wei Jie, Kulkarni Santosh S., Murray Thomas F., Aldrich Jane V., Design and synthesis of cyclic arodyn analogues by ring-closing metathesis (RCM) for kappa opioid receptor (KOP) antagonists.
  611, p. 279 - 280 2009
• International Journal of Peptide Research and Therapeutics
  Aldrich Jane V., Kumar Vivek, Dattachowdhury Bhaswati, Peck Angela M., Wang Xin, Murray Thomas F., Solid phase synthesis and application of labeled peptide derivatives
  14:4, p. 315 - 321 2008
• American Journal of Veterinary Research
  Figueiredo Monica D., Moore James N., Vandenplas Michel L., Sun Wan Chun, Murray Thomas F., Effects of the second-generation synthetic lipid A analogue E5564 on responses to endotoxin equine whole blood and monocytes
  69:6, p. 796 - 803 2008
• Brain Research
  Cao Zhengyu, George Joju, Baden Daniel G., Murray Thomas F., Brevetoxin-induced phosphorylation of Pyk2 and Src in murine neocortical neurons involves distinct signaling pathways
  1184, p. 17 - 27 2007
• American Journal of Veterinary Research
  Sun Wan Chun, Moore James N., Hurley David J., Vandenplas Michel L., Linden Joel M., Murray Thomas F., Pharmacologic characterization of novel adenosine A2A receptor agonists in equine neutrophils
  68:9, p. 981 - 987 2007
• American Journal of Veterinary Research
  Moore James N., Hurley David J., Vandenplas Michel L., Linden Joel M., Murray Thomas F., Pharmacologic characterization of novel adenosine A2A receptor agonists in equine neutrophils
  68:9, p. 981 - 987 2007
• American Journal of Veterinary Research
  Sun Wan Chun, Moore James N., Hurley David J., Vandenplas Michel L., Murray Thomas F., Effects of stimulation of adenosine A2A receptors on lipopolysaccharide-induced production of reactive oxygen species by equine neutrophils
  68:6, p. 649 - 656 2007
• Journal of Physiology
  Dravid Shashank M., Nicholson Katherine, Le Phuong, Lyuboslavsky Polina, Almonte Antoine, Murray Ernest, Mosely Cara, Barber Jeremy, French Adam, Balster Robert, Murray Thomas F., Traynelis Stephen F., Yuan Hongjie, Erreger Kevin, Subunit-specific mechanisms and proton sensitivity of NMDA receptor channel block
  581:1, p. 107 - 128 2007
• Journal of Veterinary Pharmacology and Therapeutics
  Brandon C. I., Vandenplas M., Dookwah H., Linden J., Murray T. F., Cloning and pharmacological characterization of the equine adenosine A 2A receptor
  29:4, p. 243 - 253 2006
• Journal of Veterinary Pharmacology and Therapeutics
  Brandon C. I., Vandenplas M., Dookwah H., Murray T. F., Cloning and pharmacological characterization of the equine adenosine A 3 receptor
  29:4, p. 255 - 263 2006
• Brain Research
  Yan X., Koos B. J., Kruger L., Linden J., Murray Thomas F., Characterization of [I-125]ZM 241385 binding to adenosine A(2A) receptors in the pineal of sheep brain
  1096, p. 30 - 39 2006
• Toxicology Letters
  LePage K. T., Goeger D., Yokokawa F., Asano T., Shioiri T., Gerwick W. H., Murray T. F., The neurotoxic lipopeptide kalkitoxin interacts with voltage-sensitive sodium channels in cerebellar granule neurons
  158:2, p. 133 - 139 2005
• Neuropharmacology
  LePage K. T., Ishmael J. E., Low C. M., Traynelis S. F., Murray T. F., Differential binding properties of [3H]dextrorphan and [ 3H]MK-801 in heterologously expressed NMDA receptors
  49:1, p. 1 - 16 2005
• Neuropharmacology
  LePage K. T., Ishmael J. E., Low C. M., Traynelis S. F., Murray Thomas F., Differential binding properties of [ 3H]dextrorphan and [ 3H]MK-801 in heterologously expressed NMDA receptors
  49:1, p. 1 - 16 2005
• Brain Research
  Dravid Shashank M., Baden Daniel G., Murray Thomas F., Brevetoxin augments NMDA receptor signaling in murine neocortical neurons
  1031:1, p. 30 - 38 2005
• Critical Reviews in Neurobiology
  LePage Keith T., Dickey Robert W., Gerwick William H., Jester Edward L., Murray Thomas F., On the use of neuro-2a neuroblastoma cells versus intact neurons in primary culture for neurotoxicity studies
  17:1, p. 27 - 50 2005
• Journal of Neurochemistry
  Dravid Shashank M., Baden Daniel G., Murray Thomas F., Brevetoxin activation of voltage-gated sodium channels regulates Ca 2+ dynamics and ERK1/2 phosphorylation in murine neocortical neurons
  89:3, p. 739 - 749 2004
• Brain Research
  Dravid Shashank M., Murray Thomas F., Spontaneous synchronized calcium oscillations in neocortical neurons in the presence of physiological [Mg2+]
  1006:1, p. 8 - 17 2004
• Journal of Natural Products
  Li W. I., Shioiri T., Gerwick W. H., Murray T. F., Marquez B. L., Okino T., Yokokawa F., Characterization of the Preferred Stereochemistry for the Neuropharmacologic Actions of Antillatoxin
  67:4, p. 559 - 568 2004
• Physiology and Behavior
  Miller Cheryl C., Murray Thomas F., Freeman Kimberly G., Edwards Gaylen L., Cannabinoid agonist, CP 55,940, facilitates intake of palatable foods when injected into the hindbrain
  80:5, p. 611 - 616 2004
• Journal of Medicinal Chemistry
  Vig Balvinder S., Murray Thomas F., Aldrich Jane V., Synthesis and Opioid Activity of Side-Chain-to-Side-Chain Cyclic Dynorphin A-(1-11) Amide Analogues Cyclized between Positions 2 and 5. 1. Substitutions in Position 3
  47:2, p. 446 - 455 2004
• Neuroscience Letters
  Dravid Shashank M., Murray Thomas F., Fluorescent detection of Ca2+-permeable AMPA/kainate receptor activation in murine neocortical neurons
  351:3, p. 145 - 148 2003
• Journal of Peptide Research
  Choi H., Murray T. F., Aldrich Jane V., Synthesis and evaluation of potential affinity labels derived from endomorphin-2
  61:2, p. 58 - 62 2003
• Journal of Biological Chemistry
  Wolfert Margreet A., Murray Thomas F., Boons Geert Jan, Moore James N., The origin of the synergistic effect of muramyl dipeptide with endotoxin and peptidoglycan
  277:42, p. 39179 - 39186 2002
• Journal of Medicinal Chemistry
  Kumar Vivek, Murray Thomas F., Aldrich Jane V., Solid phase synthesis and evaluation of Tyr-Tic-Phe-Phe(p-NHCOCH2Br) ([Phe(p-bromoacetamide)4]TIPP), a potent affinity label for δ opioid receptors
  45:18, p. 3820 - 3823 2002
• Brain Research
  Berman Frederick W., Murray Thomas F., LePage Keith T., Domoic acid neurotoxicity in cultured cerebellar granule neurons is controlled preferentially by the NMDA receptor Ca2+ influx pathway
  924:1, p. 20 - 29 2002
• Peptides
  Garczynski Stephen F., Brown Mark R., Shen Ping, Murray Thomas F., Crim Joe W., Characterization of a functional neuropeptide F receptor from Drosophila melanogaster
  23:4, p. 773 - 780 2002
• Wu M., Berman F. W., Murray T. F., McGough K., Jacobs R., Colsen K., Asano T., Yokokawa F., Shioiri T., Gerwick W. H., Marquez B. L., Okino T., Nogle L. M., Williamson R. T., Sitachitta N., Structure, synthesis, and biological properties of kalkitoxin, a novel neurotoxin from the marine cyanobacterium Lyngbya majuscula [24] 2000
• Journal of Steroid Biochemistry and Molecular Biology
  Evans Simon J., Murray Thomas F., Moore Frank L., Partial purification and biochemical characterization of a membrane glucocorticoid receptor from an amphibian brain
  72:5, p. 209 - 221 2000
• Journal of Steroid Biochemistry and Molecular Biology
  Evans Simon J., Murray Thomas F., Moore Frank L., Solubilization and pharmacological characterization of a glucocorticoid membrane receptor from an amphibian brain
  67:1, p. 1 - 8 1998
• Journal of Neurochemistry
  Hettinger Barbara D., Leid Mark, Murray Thomas F., Cyclopentyladenosine-induced homologous down-regulation of A1 adenosine receptors (A1AR) in intact neurons is accompanied by receptor sequestration but not a reduction in A1AR mRNA expression or G protein α-subunit content
  71:1, p. 221 - 230 1998
• European Journal of Pharmacology
  Bouvier Claudia, Avram Dorina, Peterson Valerie J., Hettinger Barbara, Soderstrom Ken, Murray Thomas F., Leid Mark, Catecholaminergic CATH.a cells express predominantly δ-opioid receptors
  348:1, p. 85 - 93 1998
• Brain Research
  Zhang Ge, Murray Thomas F., Grandy David K., Orphanin FQ has an inhibitory effect on the guinea pig ileum and the mouse vas deferens
  772:1-2, p. 102 - 106 1997
• Journal of Biochemical Toxicology
  Berman Frederick W., Murray Thomas F., Characterization of [3H]MK-801 binding to N-methyl-D-aspartate receptors in cultured rat cerebellar granule neurons and involvement in glutamate-mediated toxicity
  11:5, p. 217 - 226 1996
• Journal of Biochemical Toxicology
  Berman Frederick W., Murray Thomas F., Characterization of glutamate toxicity in cultured rat cerebellar granule neurons at reduced temperature
  11:3, p. 111 - 119 1996
• Biochemistry and Molecular Biology of Fishes
  Siebenaller Joseph F., Murray Thomas F., Chapter 8 the effects of pressure on G protein-coupled signal transduction
  5:C, p. 147 - 174 1995
• Regulatory Peptides
  Arttamangkul S., Murray TF, DeLander GE, Aldrich JV, Synthesis and opioid activity of conformationally constrained dynorphin A analogues
  54:1, p. 13 - 14 1994
• Regulatory Peptides
  Maeda DY, Murray TF, Roth JE, Aldrich JV, Synthesis of enkephalin-based affinity labels for delta opioid receptors
  54:1, p. 171 - 172 1994
• Comparative Biochemistry and Physiology -- Part B: Biochemistry and
  Siebenaller Joseph F., Murray Thomas F., The effects of hydrostatic pressure on pertussis toxin-catalyzed ribosylation of guanine nucleotide-binding proteins from two congeneric marine fish
  108:4, p. 423 - 430 1994
• Biochemistry and Molecular Biology of Fishes
  Siebenaller Joseph F., Murray Thomas F., Membrane preparation and receptor assays — adenosine
  3:C, p. 477 - 486 1994
• Journal of Medicinal Chemistry
  Choi Heekyung, Murray Thomas F., DeLander Gary E., Caldwell Valerie, Aldrich Jane V., N-Terminal Alkylated Derivatives of [d-Pro10]dynorphin A-(1-11) Are Highly Selective for k-Opioid Receptors
  35:24, p. 4638 - 4639 1992
• Journal of Neurochemistry
  Steketee Jeffery D., Striplin Caryn D., Murray Thomas F., Kalivas Peter W., Pertussis Toxin in the A10 Region Increases Dopamine Synthesis and Metabolism
  58:3, p. 811 - 816 1992
• Neuroscience Letters
  Zhang Ge, Franklin Paul H., Murray Thomas F., Anticonvulsant effect of N-ethylcarboxamidoadenosine against kainic acid-induced behavioral seizures in the rat prepiriform cortex
  114:3, p. 345 - 350 1990
• Neuropharmacology
  Eshleman A. J., Murray T. F., Dependence on γ-aminobutyric acid of pyrethroid and 4′-chlorodiazepam modulation of the binding of t-[35S] butylbicyclophosphorothionate in piscine brain
  29:7, p. 641 - 648 1990
• Proceedings of the Western Pharmacology Society
  Zhang G., Franklin P. H., Murray T. F., Activation of adenosine receptors suppresses behavioral seizures induced by kainic acid in the rat prepiriform cortex
  32 1989
• Neuropharmacology
  Sanders R. C., Murray T. F., Chronic theophylline exposure increases agonist and antagonist binding to A1 adenosine receptors in rat brain
  27:7, p. 757 - 760 1988
• Proceedings of the Western Pharmacology Society
  Leid M., Franklin P. H., Murray T. F., Characterization of cardiac A1 adenosine receptors with the antagonist radioligand 8-cyclopentyl-1,3[3H]-dipropylxanthine
  31 1988
• Neuropharmacology
  Szot Patricia, Sanders R. C., Murray T. F., Theophylline-induced upregulation of A1-adenosine receptors associated with reduced sensitivity to convulsants
  26:8, p. 1173 - 1180 1987
• Proceedings of the Western Pharmacology Society
  Murray T. F., Siebenaller J. F., Phylogenetic distribution of A1 adenosine receptors in nervous tissue
  VOL. 29 1986
• Neuropharmacology
  Murray T. F., Sylvester D., Schultz C. S., Szot P., Purinergic modulation of the seizure threshold for pentylenetetrazol in the rat
  24:8, p. 761 - 766 1985
• Neuropharmacology
  Murray T. F., Cheney D. L., Neuronal location of N6-cyclohexyl[3H]adenosine binding sites in rat and guinea-pig brain
  21:6, p. 575 - 580 1982
• Life Sciences
  Murray Thomas F., Horita Akira, Phencyclidine-induced stereotyped behavior in rats
  24:24, p. 2217 - 2225 1979
• Pharmacology, Biochemistry and Behavior
  Murray T. F., Fischer G. J., Craigmill A. L., Pharmacological and behavioral components of tolerance to LSD and mescaline in rats
  7:3, p. 239 - 244 1977

Presentations

• S. Mehrotra and T.F. Murray. Regulation of cerebrocortical neuron spontaneous Ca2+ oscillations by metabotropic glutamate receptors. Program/Poster 120.03/A86. 2015 Neuroscience Meeting Planner. Chicago, IL, Society for Neuroscience, 2015. Online 2015
• Society for Neuroscience 2014 Annual Meeting, Washington DC, "Sodium Channel Activator-stimulated Neurite Outgrowth Involves the Brain-derived Neurotrophic Factor (BDNF) - Tropomyosin related Kinase B (TrkB) Signaling Pathway 2014
• Molecular Devices Symposium, Nanjing China, "High Throughput Screening and Discovery of Marine Natural Products that Target Neuronal Ion Channels." 2014
• China Pharmaceutical University, Nanjing China, "Sodium Channel Activator-Induced Enhancement of Cerebrocortical Neuron Neurite Outgrowth Requires both GluN2B NMDA Receptors and p21 Protein (Cdc42/Rac)-activated kinase 1 (PAK1)." 2014
• Cell Biology of the Neuron, Gordon Research Center, Waterville, NH, "Sodium channel activator-induced enhancement of cerebrocortical neuron neurite outgrowth requires both GluN2B NMDA receptors and p21 protein (Cdc42/Rac)-activated kinase 1(PAK1)" 2014
• The Society for Neuroscience 2013 Annual Meeting, San Diego, CA, "Voltage-gated sodium channel activator enhancement of immature cerebrocortical neuron development requires both the N-methyl-D-aspartate receptor 2B (GluN2B) and p21 protein (Cdc42/Rac)-activated kinase 1 (PAK1)" 2013
• The Society for Neuroscience 2013 Annual Meeting, San Diego, CA "Quantification of kappa opioid receptor ligand potency and efficacy using the FLIPR Membrane Potential Assay" 2013
• BIT's 3rd Annual World Congress of Marine Biotechnology Hangzhou, China "Discovery and Characterization of Marine Natural Products that Target Neuronal Ion Channels" 2013
• College of Life Sciences, Zhejiang University, Zhijingang Campus, Hangzhou, Zhejiang Province, China "Bidirectional Influence of the Marine Natural Product, Brevetoxin, on NMDA Receptor-Dependent Neuronal Structural Plasticity" 2013
• The Society of Neuroscience 2012 Annual Meeting, New Orleans, LA, "Novel C1-cocaine analogs unlike cocaine or benztropine" 2012
• Experimental Biology, San Diego, CA 2012
• The Society of Neuroscience 2011 Annual Meeting, Washington, DC, "Kappa-opioid receptor inhibition of calcium oscillations in spinal cord neurons" 2011
• 7th Annual Ion Channel Targets, South San Francisco, CA "Novel Marine Natural Products that Mimic Neuronal Activity-Dependent Neuroplasticity" 2011
• 2011 American Society Pharmacognosy Annual Meeting, San Diego, CA "Regulation of Neuronal Ion Channel Function By Marine Natural Products" 2011
• 2011 Therapeutic Potential of Kappa Opioids in Pain and Addiction, Seattle, WA, "Kappa-opioid receptor inhibition of calcium oscillations in spinal cord neurons" 2011
• University of Iowa, College of Pharmacy, Iowa City, Iowa. "Sodium channel activators that mimic activity-dependent neuronal plasticity:Novel targets for drug discovery." 2011
• Experimental Biology, San Diego, CA, "Biphasic influence of sodium channel ativation on neuronal structural plasticity" FASEB J 3-17-11 25:1003.3 2011
• Experimental Biology, San Diego, CA, "Sodium channel activator-induced neurite outgrowth is NMDA receptor dependent and involves a TrkB-PLC{gamma}-Akt pathway" FASEB J 3-17-11 25:1003.3 2011
• Institute of Biophysics of the Chinese Academy of Sciences, Beijing, China, "Voltage-gated sodium channels regulate neurite outgrowth in developing neurons" 2010
• The Second International Symposium on Membrane Biology, Ning-Bo, China, "Novel sodium channel activators mimic activity-dependent neuronal plasticity" 2010
• Society for Neuroscience, Neuroscience Meeting Planner, San Diego, CA. "Intracelluar sodium regulation of NMDA receptor-dependent neuronal plasticity" 2010
• Society for Neuroscience, Neuroscience Meeting Planner, San Diego, CA. "Kappa opioid receptor regulation of spontaneous calcium oscillations in embryonic spinal cord neurons" 2010
• Screening Europe, Barcelona, Spain, "Voltage-gated sodium channel activators with differing efficacies stimulate neurite outgrowth in cerebrocortical neurons." 2010
• Target Discovery World Congress, San Francisco, CA, "Sodium channel activation augments NMDA receptor function and promotes neurite outgrowth in cerebrocortical neurons." 2009
• Presentation, "Adenosine as an endogenous anticonvulsant: preclinical characterization and clinical implications" at Merck & Co. 2009
• George, J. and Murray, T.F. Sodium channel activation modulates synchronized calcium oscillations and neuronal morphology in immature cerebrocortical neurons. FASEB Journal 23:946.1, 2009 2009
• "Neuroscience Research Areas of Emphasis at Creighton University School of Medicine," Jesuit Medical Colleges Symposium, St. Louis University 2009
• Presentation at University of Mississippi, "Discovery and characterization of neuroactive marine natural products: voltage-gated sodium channels as a common target" 2009
• Jabba, S., Gerwick, W.H., and Murray, T.F. Antillatoxin, a novel lipopeptide, enhances neurite outgrowth in immature cerebrocortical neurons through activation of voltage-gated sodium channels. Program # 807.2, Society for Neuroscience 2008
• "Drug Discovery Strategies and High Throughput Screening in an Academic Environment" at Galleon Pharmaceuticals, Horsham, PA 2008
• Ion Channel Targets, South San Francisco, CA, "Influence of Lipid Soluble Gating Modifier Toxins on Sodium Influx in Neocortical Neurons" 2008
• Seminar entitled "Neuronal responses to sodium channel gating modifiers: From neurotoxicity to dendritogenesis" at the Barrow Neurological Institute, Phoenix, AZ, May 20, 2008. 2008
• George, J., Cao, Z. and Murray, T.F. Brevetoxin sensitizes immature cerebrocortical neurons to NMDA receptor signaling through activation of voltage-gated sodium channels. FASEB Journal 22:721.6, 2008. 2008
• Cao, Z., George, J., Gerwick, W.H. and Murray, T.F. Voltage-dependent sodium channel gating modifier toxins produce sodium influx in neocortical neurons. #1727 The Toxicologist (Society for Toxicology) 2008. 2008
• Seminar entitled "Marine natural products as sodium channel gating modifiers: Neurotoxicants or novel therapeutics?" at Scripps Institution of Oceanography, University of California at San Diego, November 5, 2007. 2007
• Murray, T.F., Xie, J., Peterson, J. and Baden D.G. Brevetoxin activation of voltage-gated sodium channels stimulates neurite outgrowth in immature cerebrocortical neurons. Program No. 34.13. 2007 Neuroscience Meeting Planner. San Diego, CA: Society for Neuroscience, 2007. Online. 2007
• Seminar entitled "Neuronal responses to voltage-gated sodium channel activators: From neurotoxicity to dendritic development" at the Department of Neuroscience, Medical University of South Carolina, Charleston, SC, September 21, 2007. 2007
• Ion Channel Targets, Boston MA, September 10, 2007, "Evaluating Ion Channel Mechanisms in Murine Neuronal Cultures and Human Embryonic Stem Cell-Derived Neurons Using FLIPR and Flex Station." 2007
• Xie, J. Peterson, J. Murray, T.F. Brevetoxin enhanced neurite growth involves voltage-gated sodium channel activation with engagement of NMDA receptors and CaM-kinase kinase FASEB JOURNAL 21 (6): A785-A786, 2007 2007
• Murray, T.F., Yan, X., Gomez, A.P., Baden, D.G., and Benson, J.M. Brevetoxin-induced neural insult in the retrosplenial cortex of mouse brain following inhalation exposure. The Toxicologist 96, 363, 2007. 2007
• LePage, K.T., Rainier, J.D. and Murray, T.F. Gambierol acts as a functional antagonist of neurotoxin site 5 on voltage-gated sodium channels in cerebellar granule cells. The Toxicologist 96, 364, 2007. 2007
• Cao,Z., Baden, D.G. and T.F. Murray. Brevetoxin-induced phosphorylation of Pyk2 and Src in murine neocortical neurons occurs through distinct pathways Program No. 130.12. 2006 Neuroscience Meeting Planner. Atlanta, GA: Society for Neuroscience, 2006. Online. 2006
• LePage, K.T., Stice, S.L. and T.F.Murray. Activation of voltage-gated sodium channels produces Ca2+ influx in human neural progenitor cell lines derived from embryonic stem cells Program No. 130.14. 2006 Neuroscience Meeting Planner. Atlanta, GA: Society for Neuroscience, 2006. Online. 2006

Awards

• Jack L. Beal Award
  Detailed Analysis of (-)-Palmyrolide A and Some Synthetic Derivatives as Voltage-Gated Sodium Channel Antagonists. Suneet Mehrota, Brendan A. Duggan, Rodolfo Tello-Aburto, Tara D. Newar, William H. Gerwick, Thomas F. Murray, and William A. Maio* J. Nat. Prod., 2014, 77, 2553-2560. DOI: 10.1021/np500644k
  Journal of Natural Products
• Arthur E. Schwarting Award
  The Hoiamides, Structurally Intriguing Neurotoxic Lipopeptides from Papua New Guinea Marine Cyanobacteria. Hyukjae Choi, Alban R. Pereira, Zhengzu Cao, Cynthia F. Shuman, Niclas Engene, Tara Byrum, Teatulohi Matainaho, Thomas F. Murray, Alfonso Mangoni, and William H. Gerwick J. Nat. Prod.; (Article); 2010; 73(11); 1411-1421. DOI 10.1021/np100468n
  Journal of Natural Products