Sandor Lovas, PhD

Professor

Biomedical Sciences

S Lovas

Contact

School of Medicine
Biomedical Sciences
Graduate School
Biomedical Sciences (Master of Science)
Biomedical Sciences (Doctorate)
CRISS II - Criss 2 - R.305

Sandor Lovas, PhD

Professor

Biomedical Sciences

Cancer Research Focus

My lab studies the conformation-biological activity relationships in peptides/proteins that inhibit cancer growth, such as cutaneous squamous cell carcinoma and glioblastoma. We also examine the description of solution structure of polypeptides by Molecular Dynamics simulations and vibrational and/or electronic circular dichroism spectropolarimetry and the effects of weakly polar interactions on peptide/protein structures.

Cancer Research Area(s)
  • Brain Cancer
  • Drug Discovery and Development
  • Skin Cancer

Teaching Interests

  • Biophysical Chemistry

Research Focus

Conformation-biological activity relationships in peptides/proteins including GnRH, gastrin, antibacterial peptides, amyloidogenic peptides and chlorotoxins. Structural characterization of prestin. Inhibtion of biological activity of 14-3-3e protein.  Description of solution structure of polypeptides by Molecular Dynamics simulations and ab initio quantum chemical calculations. Effects of weakly polar interactions on peptide/protein structures using the above theoretical methods and vibrational  and/or electronic circular dichroism spectroscopy.
 

Department

Biomedical Sciences

Position

Professor

Books

  • American Peptide Symposia
    Gembitsky Dmitry S., Murphy Richard F., Lovas Sándor, Modulation of NK-2 receptor associated G-protein signaling by alternation of the aromatic residue at position six in neurokinin A analogs.in Peptides for the New Millenium Fields [Book Chapter] 2019
  • Understanding Biology Using Peptides
    Herédi-Szabó Krisztina, Murphy Richard F., Lovas Sándor, Antiproliferative Effect of Lamprey Gonadotropin-Releasing Hormone III on Cancer Cells from Non-Reproductive Organs [Book Chapter] 2018
  • Lovas Sandor, Watts C. R., Misfolding and Oligomerization of Amyloid Beta(1-40) 2015
  • Peptides: The Wave of the Future
    Ahmed Shawn I., Wibowo Felice, Gembitsky Dmitry S., Murphy Richard F., Lovas Sándor, Role of the C-terminal and Central Region of Gastrin for Recognition by the Human CCK2 Receptor [Book Chapter] 2001
  • Peptides: The Wave of the Future
    Tóth Gergely, Lovas Sándor, Hirst Jonathan, Murphy Richard F., Kövér Katalin E., Helix stabilizing aromatic-backbone interactions [Book Chapter] 2001
  • Peptides: The Wave of the Future
    Wibowo Felicitas I., Ahmed Shawn, Gembitsky Dmitry S., Lovas Sándor, Murphy Richard F., Human colon cancers recognize N-carboxymethyl gastrin by a non-CCK1, non-CCK2 receptor [Book Chapter] 2001
  • Peptides: The Wave of the Future
    Otvos Laszlo, Kragol Goran, Varadi Gyorgyi, Condie Barry A., Lovas Sandor, The Proline-rich antibacterial peptide family inhibits chaperone-assisted protein folding [Book Chapter] 2001
  • Murnin Mark, Lovas Sándor, Allen James M, Murphy Richard F, Organ/Tissue Preparations for the Assessment of Agonist/Antagonist Activity - 30 [Book Chapter] 1997
  • Lovas Sándor, Murphy Richard F, Molecular Modeling of Neuropeptides - 18 [Book Chapter] 1997

Articles

  • Mezo I., Gulyas E., Otvos F., Mak M., Horvath J. E., Lovas S., Turi G., Palyi I., Vincze B., Kalnay A., Vadasz Z., Seprodi J., Idei M., Toth G., Teplan I., Murphy R. F., Erratum 1998

Publications

  • FEBS letters
    Kamayirese Seraphine, Hansen Laura A., Lovas Sándor, Ligand recognition by 14‐3‐3 proteins requires negative charges but not necessarily phosphorylation 2025
  • Science advances
    Vijayakumar Sarath, Lovas Sándor, McCullumsmith Robert E, Ryan William G, Diers Jack, Tu Shu, Zallocchi Marisa, Zuo Jian, DiGuiseppi Joseph A, Dabestani Parinaz Jila, Quevedo Rene Vielman, Li Yuju, Nguyen Cassidy, Rhoda Lauren M, Imami Ali Sajid, Hamoud Abdul-Rizaq Ali, Fleegel Jonathan, In silico transcriptome screens identify epidermal growth factor receptor inhibitors as therapeutics for noise-induced hearing loss
    10:25, p. eadk2299 2024
  • International journal of molecular sciences
    Kamayirese Seraphine, Maity Sibaprasad, Hansen Laura A, Lovas Sándor, The Development of CDC25A-Derived Phosphoseryl Peptides That Bind 14-3-3ε with High Affinities
    25:9, p. 4918 2024
  • ACS omega
    Kamayirese Seraphine, Dieckman Lynne M., Hansen Laura A., Lovas Sándor, Maity Sibaprasad, Optimizing Phosphopeptide Structures That Target 14-3-3ε in Cutaneous Squamous Cell Carcinoma 2024
  • The Journal of biological chemistry
    Rudd Justin C., Hansen Laura A., Lovas Sándor, Maity Sibaprasad, Grunkemeyer James A., Snyder Joshua C., Membrane structure and internalization dynamics of human Flower isoforms hFWE3 and hFWE4 indicate a conserved endocytic role for hFWE4, p. 104945 - 104945 2023
  • The Journal of biological chemistry
    Rudd Justin, Maity Sibaprasad, Snyder Joshua, Lovas Sandor, Hansen Laura, Abstract 1432: Structural determination and internalization dynamics of human Flower isoforms
    299:3, p. 103795 2023
  • Burns William A, Lovas Sandor, Watts Charles R, Dynamic Solvent Accessible Surface Areas of Proteogenic Amino Acids as a Function of Explored Phi,Psi Dihedral Angle Space 2023
  • Carcinogenesis
    Holmes Thomas R., Rudd Justin C., Bloom Celia, Nicola Lauren, Palermo Nicholas Y., Madson Justin G., Lovas Sándor, Hansen Laura A., Al Matouq Jenan, Holmes Matti, Sioda Natasha, Targeting 14-3-3ϵ activates apoptotic signaling to prevent cutaneous squamous cell carcinoma
    42:2, p. 232 - 242 2021
  • Oncotarget
    Holmes Thomas R., Al-Matouq Jenan, Holmes Matti, Nicola Lauren, Rudd Justin C., Lovas Sándor, Hansen Laura A., Targeting 14-3-3ε-CDC25A interactions to trigger apoptotic cell death in skin cancer
    11:35, p. 3267 - 3278 2020
  • International journal of molecular sciences
    Voit-Ostricki Leah, Lovas Sándor, Watts Charles R., Conformation and domain movement analysis of human matrix metalloproteinase-2
    20:17 2019
  • Proteins
    Watts C. R., Gregory A. J., Frisbie Cole P., Lovas Sandor, Structural Properties of Amyloid Beta(1-40) Dimer Explored by Replica Exchange Molecular Dynamics Simulations
    85:6, p. 1024 - 1045 2017
  • Protein and Peptide Letters
    Knappe D., Goldback T., Hatfield M. P. D., Palermo N. Y., Weinert S., Strater N., Hoffman R., Lovas Sandor, Proline-Rich Antimicrobial Peptides Optimized for Binding to Escherichia Coli Chaperone DnaK
    23:12, p. 1061 - 1071 2016
  • Journal of Biological Chemistry
    Lovas Sandor, He David Z. Z., Liu Huizhan, Tang Jie, Pecka Jason L., Hatfield Marcus P. D., Beisel Kirk W., Glutamate Transporter Homolog-based Model Predicts That Anion-pi Interaction Is the Mechanism for the Voltage-dependent Response of Prestin
    290:40, p. 24326 - 24339 2015
  • Biopolymers
    Otvos L., Kovalszky I., Olah J., Coroniti R., Knappe D., Nollmann F. I., Hoffmann R., Wade J. D., Lovas Sandor, Surmacz E., Optimization of adiponectin-derived peptides for inhibition of cancer cell growth and signaling
    104:3, p. 155 - 166 2015
  • Frontiers in Chemistry
    Otvos Laszlo,Jr, Knappe Daniel, Hoffmann Ralf, Kovalszky Ilona, Olah Julia, Hewitson Tim D., Stawikowska Roma, Surmacz Eva, Lovas Sandor, Wade John D., Stawikowski Maciej, Cudic Predrag, Lin Feng, Development of second generation peptides modulating cellular adiponectin receptor responses
    2, p. Article 93 (15 pages) 2014
  • Hearing Research
    He David Z. Z., Ai Yu, Li Yi, Beisel Kirk W., Lovas Sandor, Prestin at year 14: progress and prospect
    311, p. 25 - 35 2014
  • Current Pharmaceutical Design
    Hatfield Marcus P. D., Lovas Sandor, Conformational sampling techniques
    20:20, p. 3303 - 3313 2014
  • Journal of Physical Chemistry. B
    Lovas Sandor, Molecular Mechanism of Misfolding and Aggregation of Amyloid Beta (13-23)
    117:20, p. 6175 - 6186 2013
  • Journal of Cell Science
    Tan Xiaodong, Pecka Jason L., Tang Jie, Lovas Sandor, Beisel Kirk W., He David Z. Z., A motif of eleven amino acids is a structural adaptation that facilitates motor capability of eutherian prestin
    125:4, p. 1039 - 1047 2012
  • Journal of Peptide Science
    Palermo N. Y., Thomas P., Murphy R. F., Lovas Sandor, Hexapeptide Fragment of Carcinoembryonic Antigen which Acts as an Agonist of Heterogeneous Ribonucleoprotein, p. 252 - 260 2012
  • Journal of Physical Chemistry. B
    Hatfield M. P., Lovas Sandor, Murphy Richard F., The CLN025 decapeptide retains a β-hairpin conformation in urea and guanidinium chloride
    115:17, p. 4971 - 4981 2011
  • BMC biotechnology
    Otvos Laszlo, Haspinger Eva, La Russa Francesca, Maspero Federica, Graziano Patrizia, Kovalszky Ilona, Lovas Sandor, Nama Kaushik, Hoffmann Ralf, Knappe Daniel, Wade John, Cassone Marco, Surmacz Eva, Design and development of a peptide-based adiponectin receptor agonist for cancer treatment.
    11, p. 90 2011
  • Biopolymers
    Otvos Laszlo, Jr., Sztodola Andras, Olah Julia, Knappe Daniel, Hoffmann Ralf, Lovas Sandor, Kovalszky Ilona, Scolaro Laura, Cassone Marco, Hatfield Marcus P. D., Beko Gabriella, Zhang Suode, Wade John D., Surmacz Eva, Peptide-Based leptin Receptor Antagonists for Cancer Treatment and Appetite Regulation
    96:2, p. 117 - 125 2011
  • Biopolymers
    Hatfield M. P., Murphy Richard F., Lovas Sandor, VCD spectroscopic properties of the beta-hairpin forming miniprotein CLN025 in various solvents
    93:5, p. 442 - 450 2010
  • Peptides
    Copps Jeffrey, Ahmed Shawn, Murphy Richard F., Lovas Sandor, Bioactivity of analogs of the N-terminal region of gastrin-17
    30:12, p. 2263 - 2267 2009
  • Peptides
    Copps Jeffrey, Murphy Richard F., Lovas Sandor, The structure of bioactive analogs of the N-terminal region of gastrin-17
    30:12, p. 2250 - 2262 2009
  • Biopolymers
    Csontos Jozsef, Murphy Richard F., Lovas Sandor, The role of weakly polar and H-bonding interactions in the stabilization of the conformers of FGG, WGG, and YGG: An aqueous phase computational study
    89:11, p. 1002 - 1011 2008
  • Journal of Computational Chemistry
    Komáromi István, Owen Michael C., Murphy Richard F., Lovas Sándor, Development of glycyl radical parameters for the OPLS-AA/L force field
    29:12, p. 1999 - 2009 2008
  • Journal of Computational Chemistry
    Csontos J., Murphy Richard F., Lovas Sandor, Tasi G., Kalman M., The effect of electron correlation on the conformational space of melatonin
    29:9, p. 1466 - 1471 2008
  • International Journal of Quantum Chemistry
    Palermo N. Y., Csontos J., Murphy Richard F., Lovas Sandor, Role of aromatic residues in stabilizing the secondary and tertiary structure of avian pancreatic polypeptide
    108:4, p. 814 - 819 2008
  • J.Comput.Chem.
    Csontos J., Palermo N. Y., Murphy Richard F., Lovas Sandor, Calculation of weakly polar interaction energies in polypeptides using density functional and local Moller-Plesset perturbation theory
    29:8, p. 1344 - 1352 2008
  • Methods in Molecular Biology
    Copps J., Murphy Richard F., Lovas Sandor, Molecular dynamics simulations of peptides
    494, p. 115 - 126 2008
  • International Journal of Peptide Research and Therapeutics
    Ötvös Ferenc, Lovas Sándor, Gembitsky Dmitry S., Murphy Richard F., Synthesis and structure-activity relationship of [Nle10] neurokinin A (4-10) analogs with constraint in the backbone and at position six
    13:1-2, p. 329 - 336 2007
  • Journal of Computational Chemistry
    Palermo N. Y., Csontos J., Owen M. C., Murphy Richard F., Lovas Sandor, Aromatic-backbone interactions in model alpha-helical peptides
    28:7, p. 1208 - 1214 2007
  • Protein and Peptide Letters
    Borics Attila, Murphy Richard F., Lovas Sándor, Conformational analysis of Ac-NPGQ-NH2 and Ac-VPaH-NH 2 by vibrational circular dichroism spectroscopy combined with molecular dynamics and quantum chemical calculations
    14:4, p. 353 - 359 2007
  • Peptides
    Copps Jeffrey, Ahmed Shawn, Lovas Sándor, Murphy Richard F., Gastrin 1-6 promotes growth of colon cancer cells through non-CCK receptors
    28:3, p. 632 - 635 2007
  • Peptides
    Copps J., Ahmed S., Murphy Richard F., Lovas Sandor, Gastrin 1-6 promotes growth of colon cancer cells through non-CCK receptors
    28:3, p. 632 - 635 2007
  • Biopolymers
    Borics A., Murphy Richard F., Lovas Sandor, Optical spectroscopic elucidation of beta-turns in disulfide bridged cyclic tetrapeptides
    85:1, p. 1 - 11 2007
  • Biopolymers
    Copps Jeffrey D., Murphy Richard F., Lovas Sandor, VCD spectroscopic and molecular dynamics analysis of the Trp-cage miniprotein TC5b
    88:3, p. 427 - 437 2007
  • Journal of Peptide Science
    Heredi-Szabo K., Murphy Richard F., Lovas Sandor, Is IGnRH-III the most potent GnRH analog containing only natural amino acids that specifically inhibits the growth of human breast cancer cells?
    12:11, p. 714 - 720 2006
  • Biopolymers
    Copps J., Murphy Richard F., Lovas Sandor, Avian pancreatic polypeptide fragments refold to native aPP conformation when combined in solution: A CD and VCD study
    83, p. 32 - 38 2006
  • Owen M., Murphy Richard F., Lovas Sandor, The conformational preference of Ca-centered protein radicals. 2006
  • Biopolymers
    Borics A., Murphy Richard F., Lovas Sandor, Optical spectroscopic elucidation of different types of b-turns in disulfide bridged cyclic tetrapeptides 2006
  • Peptides
    Ahmed Shawn, Murphy Richard F., Lovas Sándor, Importance of N- and C-terminal regions of gastrin-Gly for preferential binding to high and low affinity gastrin-Gly receptors
    26:7, p. 1207 - 1212 2005
  • Peptides
    Ahmed S., Murphy Richard F., Lovas Sandor, Importance of N- and C-terminal regions of gastrin-Gly for preferential binding to high and low affinity gastrin-Gly receptors
    26:7, p. 1207 - 1212 2005
  • Journal of Physical Chemistry A
    Chass Gregory A., Mirasol Reinard S., Setiadi David H., Tang Ting Hua, Chin Wutharath, Mons Michel, Dimicoli Iliana, Dognon Jean Pierre, Viskolcz Bela, Lovas Sándor, Penke Botond, Csizmadia Imre G., Characterization of the conformational probability of N-acetyl- Phenylalanyl-NH 2 by RHF, DFT, and MP2 computation and AIM analyses, confirmed by jet-cooled infrared data
    109:24, p. 5289 - 5302 2005
  • Peptides
    Herédi-Szabó Krisztina, Lubke Jeremiah, Toth Geza, Murphy Richard F., Lovas Sándor, Importance of the central region of lamprey gonadotropin-releasing hormone III in the inhibition of breast cancer cell growth
    26:3, p. 419 - 422 2005
  • FEBS Letters
    Ahmed Shawn, Budai Barna, Murphy Richard F., Lovas Sándor, Tóth Géza, Herédi-Szabó Krisztina, Farkas Judit, High and low affinity receptors mediate growth effects of gastrin and gastrin-Gly on DLD-1 human colonic carcinoma cells
    556:1-3, p. 199 - 203 2004
  • FEBS Letters
    Ahmed Shawn I., Farkas Judit, Tóth Géza, Murphy Richard F., Lovas Sandor, Herédi-Szabó Krisztina, Budai Barna, High and low affinity receptors mediate growth effects of gastrin and gastrin-Gly on DLD-1 human colonic carcinoma cells
    556:3-Jan, p. 199 - 203 2004
  • Journal of Molecular Structure: THEOCHEM
    Lau Suzanne K., Chass Gregory A., Lovas Sándor, Penke Botond, Csizmadia Imre G., An exploratory ab initio conformational analysis of selected fragments of nicotinamide adenine dinucleotide (NAD+). Part I
    666-667, p. 415 - 429 2003
  • Journal of Molecular Structure: THEOCHEM
    Sahai Michelle A., Lovas Sándor, Chass Gregory A., Penke Botond, Csizmadia Imre G., A modular numbering system of selected oligopeptides for molecular computations
    666-667, p. 169 - 218 2003
  • Journal of Molecular Structure. Theochem
    Sahai Michelle A., Lovas Sandor, Chass Gregory A., Penke Botond, Csizmadia Imre G., A modular numbering system of selected oligopeptides for molecular computations: using pre-computed amino acid building blocks
    666-667, p. 169 - 218 2003
  • Journal of Physical Chemistry B
    Bhattacharjee Samita, Tóth Gergely, Lovas Sándor, Hirst Jonathan D., Influence of tyrosine on the electronic circular dichroism of helical peptides
    107:33, p. 8682 - 8688 2003
  • The Journal of Physical Chemistry B
    Bhattacharjee Samita, Tóth Gergely, Hirst Jonathan D., Lovas Sándor, Influence of Tyrosine on the Electronic Circular Dichroism of Helical Peptides
    107:33, p. 8682 - 8688 2003
  • Journal of Physical Chemistry. B
    Bhattacharjee S., Toth Gergely, Lovas Sandor, Hirst D. J., Influence of Tyrosine on the Electronic Circular Dichroism of Helical Peptides
    107:33, p. 8682 - 8688 2003
  • Biopolymers
    Borics Attila, Murphy Richard F., Lovas Sandor, Fourier transform vibrational circular dichroism as a decisive tool for conformational studies of peptides containing tyrosyl residues
    72:1, p. 21 - 24 2003
  • Journal of the Chemical Society. Perkin Transactions 2
    Keglevich György, Körtvélyesi Tamás, Forintos Henrietta, Lovas Sándor, Structure and stability of oxaphosphetes formed as intermediates in the reaction of tertiary phosphine oxides and acetylenic derivatives
    2:10, p. 1645 - 1646 2002
  • European Journal of Biochemistry
    Kragol G., Hoffmann R., Lovas Sandor, Chattergoon M. A., Rosengren K. J., Montaner L. J., Otvos L., Condie B. A., Cudic M., Bulet P., Identification of crucial residues for the antibacterial activity of the proline-rich peptide, pyrrhocoricin
    269:17, p. 4226 - 4237 2002
  • European Journal of Biochemistry
    Kragol Goran, Hoffmann Ralf, Chattergoon Michael A., Lovas Sandor, Rosengren K. Johan, Cudic Mare, Bulet Philippe, Condie Barry A., Montaner Luis J., Otvos Laszlo, Identification of crucial residues for the antibacterial activity of the proline-rich peptide, pyrrhocoricin
    269:17, p. 4226 - 4237 2002
  • Journal of the American Chemical Society
    Toth Gergely, Murphy Richard F., Lovas Sandor, Investigation of aromatic-backbone amide interactions in the model peptide acetyl-phe-gly-gly-N-methyl amide using molecular dynamics simulations and protein database search
    123:47, p. 11782 - 11790 2001
  • Journal of the American Chemical Society
    Tóth G., Murphy R. F., Lovas S., Investigation of aromatic-backbone amide interactions in the model peptide Acetyl-Phe-Gly-Gly-N-Methyl amide using molecular dynamics simulations and protein database search
    123:47, p. 11782 - 11790 2001
  • The journal of peptide research : official journal of the American Peptide Society
    Ahmed S I, Wibowo F, Gembitsky D S, Bozsó Z, Murphy R F, Lovas S, Importance of the C-terminal Phenylalanine of Gastrin for Binding to the Human CCK2 Receptor
    58:4, p. 332 - 337 2001
  • Protein Engineering
    Toth Gergely, Murphy Richard F., Lovas Sandor, Stabilization of local structures by pi-CH and aromatic-backbone amide interactions involving prolyl and aromatic residues
    14:8, p. 543 - 547 2001
  • British Journal of Cancer
    Murphy Richard F., Cluck Michael W., Lovas Sandor, Otvös F., Schally A. V., Permert J., Larsson J., Knezetic Joseph A., Adrian Thomas E., Otvos Ferenc, Pancreatic cancer cells require an EGF receptor-mediated autocrine pathway for proliferation in serum-free conditions
    84:7, p. 926 - 935 2001
  • Journal of Biomolecular Structure & Dynamics
    Watts Charles R., Mezei M., Murphy Richard F., Lovas Sandor, Conformational space comparison of GnRH and IGnRH-III using molecular dynamics, cluster analysis and Monte Carlo thermodynamic integration
    18:5, p. 733 - 748 2001
  • Biochemistry
    Kragol G., Lovas Sandor, Varadi G., Condie B. A., Hoffmann R., Otvos L., The antibacterial peptide pyrrhocoricin inhibits the ATPase actions of DnaK and prevents chaperone-assisted protein folding
    40:10, p. 3016 - 3026 2001
  • Biochemistry
    Kragol G., Lovas S., Varadi G., Condie B. A., Hoffmann R., Otvos L., The antibacterial peptide pyrrhocoricin inhibits the ATPase actions of DnaK and prevents chaperone-assisted protein folding
    40:10, p. 3016 - 3026 2001
  • Protein Engineering
    Tóth G., Murphy R. F., Lovas S., Stabilization of local structures by π-CH and aromatic-backbone amide interactions involving prolyl and aromatic residues
    14:8, p. 543 - 547 2001
  • Drugs of the Future
    Pályi I., Vincze B., Mezö I., Pató J., Kálnay A., Gaál D., Seprödi J., Hudecz F., Mezö G., Lovas S., Murphy R. F., GnRH analog conjugates with high anticancer selectivity
    26:1, p. 51 - 59 2001
  • Journal of Biomolecular Structure and Dynamics
    Watts Charles R., Lovas Sándor, Mezei Mihaly, Murphy Richard F., Conformational space comparison of GnRH and lGnRH-III using molecular dynamics, cluster analysis and Monte Carlo thermodynamic integration
    18:5, p. 733 - 748 2001
  • Letters in Peptide Science
    Bozso Z., Toth G., Murphy R. F., Lovas S., Difficulties in coupling to conformationally constrained aromatic amino acids
    7:3, p. 157 - 163 2000
  • Biochemistry
    Otvos L., Blaszczyk-Thurin M., Rogers M. E., Consolvo P. J., Insug O., Condie B. A., Lovas S., Bulet P., Interaction between heat shock proteins and antimicrobial peptides
    39:46, p. 14150 - 14159 2000
  • Cell Proliferation
    Kalnay A., Mihalik R., Mezo I., Pato J., Seprodi J., Lovas Sandor, Murphy Richard F., Palyi I., Vincze B., Influence on antiproliferative activity of structural modification and conjugation of gonadotropin-releasing hormone (GnRH) analogues
    33:5, p. 275 - 285 2000
  • Journal of Medicinal Chemistry
    Gembitsky Dmitry S., Murnin Mark, Ötvös Ferenc L., Allen James, Murphy Richard F., Lovas Sándor, Importance of the aromatic residue at position 6 of [Nle10]neurokinin A(4-10) for binding to the NK-2 receptor and receptor activation
    42:15, p. 3004 - 3007 1999
  • Journal of Peptide Research
    Ötvös F., Murphy R. F., Lovas Sándor, Coupling difficulty following replacement of Tyr with HOTic during synthesis of an analog of an EGF B-loop fragment
    53:3, p. 302 - 307 1999
  • Proteins: Structure, Function and Genetics
    Watts Charles R., Lovas Sándor, Murphy Richard F., Molecular dynamics simulations of epidermal growth factor and transforming growth factor-α structures in water
    33:3, p. 396 - 407 1998
  • Journal of Peptide Research
    Lovas Sándor, Pályi I., Vincze B., Horváth J., Kovács M., Mezö I., Tóth G., Teplán I., Murphy R. F., Direct anticancer activity of gonadotropin-releasing hormone-III
    52:5, p. 384 - 389 1998
  • Methods in molecular biology (Clifton, N.J.)
    Tóth G., Otvös F., Lovas S., Tritium labeling of neuropeptides.
    73, p. 219 - 230 1997
  • Methods in molecular biology (Clifton, N.J.)
    Lovas S., Murphy R. F., Molecular modeling of neuropeptides.
    73, p. 209 - 217 1997
  • Methods in molecular biology (Clifton, N.J.)
    Murnin M., Lovas S., Allen J. M., Murphy R. F., Organ/tissue preparations for the assessment of agonist/antagonist activity.
    73, p. 343 - 352 1997
  • Helvetica Chimica Acta
    Ötvös Ferenc, Tóth Géza, Lovas Sándor, Simon Csaba, Hosztafi Sándor, 13. Synthesis and tritium labelling of 6β-amino-4,5α-epoxyraorphinans and their 14-hydroxy derivatives as potential affinity labelling probes with μ opioid agonist activity
    79:1, p. 133 - 136 1996
  • European Journal of Biochemistry
    Szendrei Gyorgyi I., Nyéki Olga, Schön Istvan, Otvos Laszlo, Fabian Heinz, Mantsch Henry H., Lovas Sandor, Aspartate‐Bond Isomerization Affects the Major Conformations of Synthetic Peptides
    226:3, p. 917 - 924 1994
  • Biochemical Society Transactions
    Lovas S., Smith D. D., Murnin M., Allen J., Murphy R. F., Structure-activity relationships of para-substituted Phe analogues of [Nle10]NKA(4-10)
    22:1, p. 5S 1994
  • Journal of Molecular Structure
    Lovas Sándor, Murphy Richard F., Solvated structure analysis of a conformationally restricted analogue of phenylalanine in a dipeptide model by the AM1-SM2 method
    311, p. 297 - 304 1994
  • Journal of Molecular Structure: THEOCHEM
    Lovas Sándor, Murphy Richard F., Solvated structure analysis of a conformationally restricted analogue of phenylalanine in a dipeptide model by the AM1-SM2 method
    311, p. 297 - 304 1994
  • Peptides
    Badgery-Parker Tim, Lovas Sandor, Conlon J. Michael, Burcher Elizabeth, Receptor binding profile of neuropeptide γ and its fragments
    14:4, p. 771 - 775 1993
  • Journal of Molecular Structure. Theochem
    Borics Attila, Chass Gregory A., Csizmadia Imre G., Murphy Richard F., Lovas Sandor, The benefits of a pre-computed amino acid structure database in quantum chemical geometry optimizations of β-turns of peptides
    666-667:0, p. 355 - 359 -0001

Federal

  • NSF-EPSCoR Major Research Research Instrumentation Program:
    High-Performance Computing Cluster for Biomolecular Calculations

  • NSF-EPSCoR Major Research Research Instrumentation Program,
    Project title: A high-throughput multi-user Biacore surface plasmon resonance system for studying biomolecular and biochemical interactions.

Other

  • NSF-EPSCoR Major Research Research Instrumentation Program:
    High-Performance Computing Cluster for Biomolecular Calculations

State

  • LB595 Program; Project Title: Molecular Mechanisms and Novel Targets in Cancer. Project PI: Novel therapeutic targets for nonmelanoma skin cancer Dates: 7/1/14-6/30/19; Role: collaborator