Director, Research Compliance Office
Professor
![J Knezetic](/sites/default/files/styles/card_contact/public/2021-12/SOM_Knezetic_Joe.jpg?itok=1SY7inMQ)
Contact
Joseph A . Knezetic, PhD
Director, Research Compliance Office
Professor
Department
Pathology
Position
Professor
Books
- Lynch Jane F., Lynch Syndrome as a Model for Identification of Hereditary High-Risk Patients [Book Chapter] 2013
- Lynch Jane F., Hereditary Factors in Endometrial Cancer [Book Chapter] 2007
Publications
- Head & Neck
Feldman R., Molecular Profiling of Head and Neck Squamous Cell Carcinoma
38:Supplement 1, p. E1625 - E1638 2016 - Expert Opinion on Medical Diagnostics
Lynch Henry T., Diagnosing Lynch Syndrome in Absence of Colorectal Cancer
6:6, p. 485 - 488 2015 - Current Treatment Options in Oncology
Lynch Henry T., Genetics, biomarkers, hereditary cancer syndrome diagnosis, heterogeneity and treatment: a review
15:3, p. 429 - 442 2014 - Journal of clinical oncology
Feldman Rebecca, Molecular profiling of HPV-positive and -negative HNSCC
32:15_suppl, p. 6080 - 6080 2014 - Expert Opinion on Medical Diagnostics
Lynch Henry T., Diagnosing lynch syndrome in absence of colorectal cancer
6:6, p. 485 - 488 2012 - Seminars in Oncology
Adonizio Christian, Thirty-Nine-Year-Old With Familial Colon Cancer, and Variant of Undetermined Significance in MSH6
39:2, p. 125 - 131 2012 - Human Pathology
Gatalica Zoran, Renal medullary carcinomas: histopathologic phenotype associated with diverse genotypes
42:12, p. 1979 - 1988 2011 - Applied Immunohistochemistry & Molecular Morphology
Stevens T. M., Detection of High-Risk HPV in Head and Neck Squamous Cell Carcinomas: Comparison of Chromogenic In Situ Hybridization and a Reverse Line Blot Method
19:6, p. 1574 - 1578 2011 - Laboratory Medicine
Carlos E. F. C., Use of 16s rRNA Gene Sequencing to Identify a Case of Pediococcus parvulus Bacteremia in a Patient with Metastatic Testicular Cancer
41:2, p. 93 - 95 2010 - Cancer Genetics and Cytogenetics
Locker Gershon Y., The I1307K APC polymorphism in Ashkenazi Jews with colorectal cancer
169:1, p. 33 - 38 2006 - Journal of Steroid Biochemistry and Molecular Biology
Rapuri Prema B., Association between Vitamin D receptor polymorphisms and the rate of bone loss in elderly women���importance of adjusting for dietary and lifestyle factors
89-90:5-Jan, p. 503 - 506 2004 - Molecular and Cellular Endocrinology
Cluck M. W., Amylin gene expression mediated by cAMP/PKA and transcription factors HNF-1 and NFY
210:1-2, p. 63 - 75 2003 - American Journal of Gastroenterology
Lynch Jane F., Multiple primary cancer, including transitional cell carcinoma of the upper uroepithelial tract in a multigeneration hnpcc family: molecular genetic, diagnostic, and management implications
98:3, p. 664 - 670 2003 - Blood
Staplin William R., BVL-1-like VL30 promoter sustains long-term expression in erythroid progenitor cells
101:5, p. 1798 - 1800 2003 - Archives of Insect Biochemistry and Physiology
Hart S. J., Cloning and tissue distribution of two Na+/H+ exchangers from the Malpighian tubules of Aedes aegypti
51:3, p. 121 - 135 2002 - Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis
Tanko Q., A hMLH1 genomic mutation and associated novel mRNA defects in a hereditary non-polyposis colorectal cancer family
503:1-2, p. 37 - 42 2002 - Pancreas
Thomas Deborah L., The role of oxygen-derived free radicals and nitric oxide in cytokine-induced antiproliferation of pancreatic cancer cells
24:2, p. 161 - 168 2002 - Blood Cells, Molecules, &Diseases
Staplin William R., Conserved, erythropoietin-responsive VL30 promoters isolated from erythroid progenitor cells
28:2, p. 275 - 282 2002 - Cancer
Lynch Jane F., Phenotypic variation in eight extended CDKN2A germline mutation familial atypical multiple mole melanoma-pancreatic carcinoma-prone families - The familial atypical multiple mole melanoma-pancreatic carcinoma syndrome
94:1, p. 84 - 96 2002 - Pancreas
Murphy Leon O., Receptors and ligands for autocrine growth pathways are up-regulated when pancreatic cancer cells are adapted to serum-free culture
22:3, p. 293 - 298 2001 - British Journal of Cancer
Murphy Richard F., Pancreatic cancer cells require an EGF receptor-mediated autocrine pathway for proliferation in serum-free conditions
84:7, p. 926 - 935 2001 - Journal of Clinical Endocrinology and Metabolism
Liu Jian, The intracellular mechanism of insulin resistance in pancreatic cancer patients
85:3, p. 1232 - 1238 2000 - Biochemical and biophysical research communications
Ding Xian-Zhong, Lipoxygenase Inhibitors Abolish Proliferation of Human Pancreatic Cancer Cells
261:1, p. 218 - 223 1999 - Cancer Genetics and Cytogenetics
Ichikawa Yoshihito, Microsatellite Instability and Expression of MLH1 and MSH2 in Normal and Malignant Endometrial and Ovarian Epithelium in Hereditary Nonpolyposis Colorectal Cancer Family Members
112:1, p. 2 - 8 1999 - Diseases of the Colon and Rectum
Thorson Alan G., A Century of Progress in Hereditary Nonpolyposis Colorectal Cancer (Lynch Syndrome)
42:1, p. 1 - 9 1999 - Calcified Tissue International
Kinyamu H. K., Effect of vitamin D receptor genotypes on calcium absorption, duodenal vitamin D receptor concentration, and serum 1,25 dihydroxyvitamin D levels in normal women
60:6, p. 491 - 495 1997 - Clinical nutrition (Edinburgh, Scotland)
Skullman S., Malnutrition increases m-RNA expression of EGF and EGF-receptor in liver tissue
13, p. 6 - 7 1994 - Molecular and cellular biology
Knezetic Joseph A., Mechanism of Developmental Regulation of απ, the Chicken Embryonic α-Globin Gene
13:8, p. 4632 - 4639 1993 - Felsenfeld G, DEVELOPMENTAL REGULATION OF CHICKEN GLOBIN GENE-EXPRESSION 1991
- Molecular and cellular biology
Knezetic Joseph A., Identification and Characterization of a Chicken α-Globin Enhancer
9:3, p. 893 - 901 1989 - Progress in clinical and biological research
Felsenfeld G, Regulatory protein action in the neighborhood of chicken globin genes during development
316A, p. 73 - 87 1989 - Cell
Knezetic Joseph A., The presence of nucleosomes on a DNA template prevents initiation by RNA polymerase II in vitro
45:1, p. 95 - 104 1986
Presentations
- Grand Rounds titled What's Up with the Rae Family, Omaha, NE 2017
- CP Lecture - Cytogenetics (H68; C7) (CUMC-OMA) 2016
- CP Lecture Series - Pearls - Micro-Mol Cavalieri, Knezetic (CUMC-OMA) 2016
- Pathology Grand Rounds 2008
- American Cancer Society Colossal Colon Exhibit Presentation 2005
- Department of Pathology Grand Rounds 2005
- Red Cell Gordon Conference 2001
- Fourth Annual Meeting of The American Society of Gene Therapy "Assessment of VL30 Erythropoietin Responsive Promoters for Erythroid Gene Therapy". 2001
- American Society for Microbiology, Missouri Valley Branch "Assessment of VL30 Erythropoietin Responsive Promoters for Erythroid Gene Therapy. 2001
- Creighton Cardiac Fellows - Cellular and Molecular Biology of Cardiovascular Disease Lecture Series "Cloning" 2001
- Creighton Cardiac Fellows - Cellular and Molecular Biology of Cardiovascular Disease Lecture Series & Regulation of Transcription and Translation. 2001
- Second Midwest Regional Meeting of The American Association for The Advancement of Science "Assessment of VL30 Erythropoietin Responsive Promoters for Erythroid Gene Therapy." 2000
- Second Midwest Regional Meeting of The American Association for The Advancement of Science & Nucleosome Positioning at The Developmentally Regulated Alpha-Pi Globin Promoter 2000
- 11th Conference on Hemoglobin Switching 1999
- Red Cell Gordon Conference 1999
- 2nd Annual Meeting of the American Society of Gene Therapy 1999
- Seminar at the Omaha VA Research Center 1999
Foundation/Association
Health Future Foundation - Development Regulation of Hemoglobin Genes
Health Futures Foundation Grant - Erythroid VL30: Gene Therapy for Globin Expression
Federal
Biomedical Research Support Grant - Mutagenesis of a Hemoglobin Enhancer
National Institute of Health Supplemental Grant - Treatment for Osteoporosis of the Hip-Supplement
National Institutes of Health - EDRN: The Hereditary Cancer Clinical Center
National Institutes of Health - Phenotypic and Psychosocial Study of the I1307K Mutation
National Institutes of Health - Intracellular pH Homeostasis in Malpighian Tubles
State
American Heart Association (NE Affiliate) Manipulating the Development Control of Hemoglobin Gene Regulation
State of Nebraska Cancer and Smoking - Related Disease Grant - Shared Instrumentation for Molecular Biology in Cancer Research
State of Nebraska Cancer and Smoking - Related Disease Grant - Abnormal Beta-Cell Gene Regulation in Pancreatic Cancer
State of Nebraska Cancer and Smoking Related-Disease Grant - Gastrin and Colonic Cancer
State of Nebraska Cancer and Smoking Related-Desease Grant - Autocrine Growth Factors in Pancreatic Cancer
State of Nebraska Cancer and Smoking Related-Disease Grant
State of Nebraska Cancer and Smoking Related-Disease Grant - Peptide Biosynthesis in Tumor Cells
State of Nebraska Cancer and Smoking Related-Disease Grant - Hereditary Cancer Program Grant
State of Nebraska Cancer and Smoking Related-Disease Grant - Cancer Research Molecular Biology Core Facility
State of Nebraska Cancer and Smoking Related-Disease Grant - Metabolic Interactions of Pancreatic Cancer Cells: Implication for Cachexia
State of Nebraska Cancer and Smoking Related-Disease Grant - Tobacco Smoke Exposure and Tachykinin Expression
State of Nebraska LB 692 Grant - Clinical Translation of the American Founder Mutation
State of Nebraska LB 595 Grant - MTHFR Polymorphisms and Cancer in Barret's Esophogus
Awards
- 25 year service recognition award
Received 25 year service recognition from Creighton University.
Creighton University - Dedicated Teacher Award, School of Medicine, Creighton University, Omaha, Nebraska.
Dedicated Teacher Award, School of Medicine, Creighton University, Omaha, Nebraska. - Successful inspection led for Creighton University’s full accreditation for five years by the Association for the Accreditation of Human Research Protection Programs, Inc. (AAHRPP)
Successful inspection led for Creighton University’s full accreditation for five years by the Association for the Accreditation of Human Research Protection Programs, Inc. (AAHRPP).